Fintech PR
Antag Therapeutics Announces €80 Million Series A Financing
— Round led by Versant Ventures with participation from founding investor Novo Holdings and new investors SR One, Dawn Biopharma and Pictet–
–Entering Phase I testing for next-generation weight loss therapy by antagonizing GIPR–
COPENHAGEN, Denmark, Dec. 4, 2024 /PRNewswire/ — Antag Therapeutics, a next-generation biopharmaceutical company pioneering novel treatments for obesity, today announced the closing of an €80 million Series A financing. The round was led by Versant Ventures, with participation from Novo Holdings, SR One, Dawn Biopharma (a platform controlled by KKR), Pictet, Longview Ventures (an affiliate of Broadview Ventures), and Export and Investment Fund of Denmark (EIFO). The funds will support the clinical development of AT-7687, a novel, once-weekly subcutaneous antagonist of the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR), and also fueling the expansion of Antag’s pipeline of monthly injectable therapies.
GLP-1-based therapies have revolutionized obesity management, but for some patients can cause tolerability issues, loss of muscle mass, and suboptimal weight-loss. This highlights the need for complementary pharmacological approaches.
The genetic basis for antagonizing GIPR is clear. Individuals with naturally occurring genetic GIPR variants that reduce its activity have lower BMI and body fat percentages, resulting in a leaner phenotype compared to those with normal GIPR function.
The development of Antag’s lead molecule is rooted in the groundbreaking identification of an endogenous GIPR antagonist by University of Copenhagen professors Jens Holst, renowned for his discovery of GLP-1, and Mette Rosenkilde. Both co-founded Antag and bring extensive expertise in incretin biology spanning decades. Professor Holst also chairs Antag’s scientific advisory board.
AT-7687 is a peptide designed to be co-administrated with current or future obesity therapies including GLP-1 medicines to deliver superior weight loss and metabolic benefits. This flexibility in dosing provides multiple advantages over competing GIPR blockers such as antibodies directly conjugated to GLP-1. These include the ability to optimally drug each target for maximal efficacy and tolerability. In addition, AT-7687 also can be used as a single agent in the maintenance setting.
In non-human primate studies, AT-7687 plus a GLP-1 produced best-in-industry weight loss. Furthermore, AT-7687 improved glycemic control and lipid profiles independent of weight changes. Importantly, these benefits were achieved without gastrointestinal side effects.
The U.S. Food and Drug Administration (FDA) recently accepted Antag’s Investigational New Drug (IND) application for AT-7687, setting the stage for clinical development to begin early next year. The trials will explore the effects of AT-7687 as both a monotherapy and in combination with a GLP-1 receptor agonist in obese patients. Antag’s pipeline also includes combinations beyond GLP-1 receptor agonists and a follow-on molecule that enables monthly administration.
“The backing of such a strong syndicate of global investors is a testament to our pioneering approach to developing novel therapies for patients with obesity,” said Alexander Hovard Sparre-Ulrich, Ph.D., CEO and co-founder of Antag. “Coupled with our recent IND clearance, this investment allows us to accelerate the development of AT-7687 towards important clinical milestones. We believe our first-in-class peptide’s weight loss profile and flexible dosing will be key drivers of differentiation.”
“Antag’s peptides will have important advantages given their ability to be used alone or optimally combined with other incretin-based agents, in both weekly or monthly formats,” said Alex Mayweg, Ph.D., Managing Director at Versant and an Antag board member. “GIP receptor antagonism is just beginning to reveal its incredible potential, both in diabetic and non-diabetic obesity, and we are pleased to be at the forefront of this developing field.”
“Novo Holdings was the first investor in Antag and we were excited by great science and a world-renowned founder team,” said Jeroen Bakker, Partner, Seed Investments, Novo Holdings. “We are proud to close this Series A round, which brings several blue-chip investors on board. This funding marks a pivotal step in advancing Antag’s pipeline, which we are confident could play a crucial role in further improving the lives of people with obesity.”
About Antag Therapeutics
Antag Therapeutics is a clinical-stage biopharmaceutical company committed to discovering and developing novel therapies for obesity and cardiometabolic diseases through GIP receptor antagonism. As a pioneer in exploring the potential of GIP receptor antagonists, the company is dedicated to advancing science and improving patient outcomes by delivering groundbreaking solutions that address unmet medical needs. For more information, please visit https://antagtherapeutics.com.
About Versant Ventures
Versant Ventures is a leading healthcare venture capital firm committed to helping exceptional entrepreneurs build the next generation of great companies. The firm’s emphasis is on biotechnology companies that are discovering and developing novel therapeutics. With $5.5 billion under management and offices in the U.S., Canada and Europe, Versant has built a team with deep investment, operating and R&D expertise that enables a hands-on approach to company building. Since the firm’s founding in 1999, more than 100 Versant companies have achieved successful acquisitions or IPOs. For more information, please visit www.versantventures.com.
About Novo Holdings A/S
Novo Holdings is a holding and investment company that is responsible for managing the assets and the wealth of the Novo Nordisk Foundation. The purpose of Novo Holdings is to improve people’s health and the sustainability of society and the planet by generating attractive long-term returns on the assets of the Novo Nordisk Foundation. Wholly owned by the Novo Nordisk Foundation, Novo Holdings is the controlling shareholder of Novo Nordisk A/S and Novonesis A/S (Novozymes A/S) and manages an investment portfolio with a long-term return perspective. In addition to managing a broad portfolio of equities, bonds, real estate, infrastructure and private equity assets, Novo Holdings is a world-leading life sciences investor. Through its Seed, Venture, Growth, Asia, Planetary Health and Principal Investments teams, Novo Holdings invests in life science companies at all stages of development. As of year-end 2023, Novo Holdings had total assets of EUR 149 billion. www.novoholdings.dk
About the Novo Nordisk Foundation
Established in Denmark in 1924, the Novo Nordisk Foundation is an enterprise foundation with philanthropic objectives. The vision of the Foundation is to improve people’s health and the sustainability of society and the planet. The Foundation’s mission is to progress research and innovation in the prevention and treatment of cardiometabolic and infectious diseases as well as to advance knowledge and solutions to support a green transformation of society.
View original content:https://www.prnewswire.co.uk/news-releases/antag-therapeutics-announces-80-million-series-a-financing-302321184.html
- A study by the international firm Bloom Consulting indicates a remarkable growth in searches in both sectors.
SAN JOSÉ, Costa Rica, Dec. 4, 2024 /PRNewswire/ — A new analysis of Costa Rica’s identity and digital footprint reveals that the country has consolidated its position by showing significant growth in tourism and exports, according to the 2022-2023 study conducted by Bloom Consulting for esencial COSTA RICA.
Based on more than 12.4 million searches, this report highlights how Costa Rica has managed to capture global interest in key areas such as tourism, investment, and exports. In addition, it underlines the country’s alignment with the principles of sustainability, a central issue for Costa Rica at the global level. In particular, the aspects of renewable energy, carbon neutral and sustainable products occupy a prominent place in international searches, reflecting the growing perception of the country as a leader in the fight against climate change and in the use of clean technologies, aligning with the 2035 Strategy of esencial COSTA RICA that seeks to consolidate the country as a world leader in sustainability.
“This fingerprint study is an invaluable tool to understand how Costa Rica is perceived globally and which aspects generate the most interest in key sectors. It allows us to fine-tune our strategies, projecting the value of Costa Rica in a way that connects with those seeking authentic and reliable experiences in a destination of quality and sustainability, “commented Adriana Acosta, Director of esencial COSTA RICA.
Tourism-related searches reached 11 million, positioning Costa Rica as one of the most attractive destinations in the world. The United States leads with almost 50% of these searches, followed by Canada and Germany. Ecotourism, surfing, and luxury tourism niches remain strategic, and searches related to sustainable activities, such as bird watching, hiking, and tourism in national parks.
In addition to its strong performance in tourism, Costa Rica has recorded a significant 8% increase in export-related searches. Products such as coffee, flowers and cocoa are the most sought after, with notable increases such as 20% in cocoa searches and 16% in coffee. This shows the competitiveness of Costa Rican exportable supply in international markets, particularly in Europe and North America.
Investment searches grew 17%, highlighting topics such as “labor costs,” “port infrastructure,” and “clean energy.” These data confirm the growing interest of international investors in Costa Rica, positioning it as an attractive destination for the development of its operations.
One of the highlights of the study is the strength of Costa Rica’s digital footprint. Content generated by official sources in the country appears in 83% of searches, which ensures that international perception is aligned with Costa Rica’s real offer.
The institutions that are part of the governance of the Country Brand play a key role in this positioning, managing reliable and up-to-date information in strategic sectors such as tourism, investment and exports.
The analysis also shows how Costa Rica has recovered and surpassed pre-pandemic levels of global interest, particularly in tourism, with a 42% growth in searches. This increase is driven by the reactivation of tourism in key markets such as the United States and Europe, which indicates a strong return of this activity after the pandemic.
“One of the objectives of the 2035 Strategy of esencial COSTA RICA is for our country to consolidate its global positioning as an example of sustainability and fight against climate change; and this new digital footprint study allows us to continue evaluating the perceptions of consumers who seek Costa Rica for different objectives, to continue working on those messages,” Acosta concluded.
With a robust digital identity and an effective content strategy, Costa Rica continues to consolidate its presence in key markets, attracting both tourists and investors and exporters from all over the world, which generates new opportunities for economic development and well-being for Costa Ricans.
Photo – https://mma.prnewswire.com/media/2572530/shutterstock_1703256913.jpg
View original content:https://www.prnewswire.co.uk/news-releases/costa-ricas-digital-identity-reflects-its-international-growth-302323145.html
Fintech
Fintech Pulse: Your Daily Industry Brief (Axos Bank, Global Trading Network, Fonepay, Compass Plus Technologies, Instacoins)
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Source: Axos Bank.
Brazil’s Largest Drug Gang Under Investigation for Fintech Infiltration
Brazilian authorities are probing the country’s largest drug gang for using fintech platforms to launder money. This investigation highlights concerns over the growing use of digital financial tools by organized crime. The gang allegedly exploited fintech’s lack of stringent oversight compared to traditional banking, raising red flags about regulatory gaps in the digital financial landscape.
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Source: PR Newswire.
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Source: Fintech Futures.
Instacoins Partners with Luxury Brands for Digital Payments
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Source: PR Newswire.
The post Fintech Pulse: Your Daily Industry Brief (Axos Bank, Global Trading Network, Fonepay, Compass Plus Technologies, Instacoins) appeared first on News, Events, Advertising Options.
Bety is a decentralized casino and sportsbook platform that supports Bitcoin deposits and withdrawals. It is owned and operated by 12 Stars International Gaming Solutions Limited, a company established in Seychelles.
Bety, one of the leading Web3 betting platforms with a decentralized approach to casinos and sportsbooks, has unveiled its enhanced offer, boasting over 20,000 crypto casino games, sports, and eSports events. The platform aims to become one of the top Bitcoin casinos with a fair, transparent, and unmatched gaming experience for everyone
Blockchain technology is a catalyst for innovation in all sectors, and online casino gaming is no exception. The growing adoption of cryptocurrency into the mainstream supports the emergence of groundbreaking platforms in digital entertainment. Bety is one of the major players spearheading this revolution by offering secure and accessible gaming experiences to change how people interact with online gambling services.
The Advantages of Web3 Betting
Traditional online casinos have been around since the early days of the Internet. However, they have always faced the same challenges, such as slow payouts and high deposit/withdrawal fees. Moreover, users have often complained about the improvable fairness of game bets and their outcomes.
Web3 betting solves these issues and takes online casino gaming to the next level through blockchain gaming. Its use of decentralized ledger technology ensures a transparent gaming experience for all users. It also accelerates deposit and withdrawal times at considerably lower costs than what traditional casinos practice.
The processing times for deposits at traditional and crypto casinos are similar, often occurring instantly. However, there is a significant difference in withdrawal times between conventional online casinos and blockchain-based casinos.For example, traditional casinos can take several days to process withdrawals. Users often have to wait up to 3 days to transfer winnings to their credit/debit cards and 7 days via bank transfers. On the other hand, crypto casinos process payouts in only a few minutes, sometimes instantly, depending on the blockchain network’s congestion. This remarkable speed allows players to access their earnings faster and enhances the user experience.
The Rise of Blockchain Gaming
Blockchain gaming is a game-changer for the online casino experience. This technology offers unprecedented levels of trust and transparency. Thanks to its decentralized nature, players from various regions can play in complete anonymity and privacy. Furthermore, the lack of a centralized authority enhances game insights. It sets the stage for provably fair game mechanics, thus empowering players to make informed choices.Bety is an innovative blockchain gaming platform that employs the Provable Fairness concept, which is fundamental for Web3 betting. The platform ensures that game outcomes are determined randomly and cannot be manipulated by the operator or any other party. Therefore, Bety guarantees equal winning odds for all players.
Innovation and Accessibility
Bety stands out as a popular crypto casino with a rich selection of classic casino games and sports events catering to high-end players. The platform excels through its user-centered approach, which includes various bonuses, an exclusive VIP program, and 24/7 customer support.Moreover, Bety embraces the latest technological advances by incorporating the many benefits of blockchain networks, such as Bitcoin payments. The platform supports quick Bitcoin deposits and withdrawals, offering higher privacy and accessibility than traditional payment methods, such as debit or credit cards.
Hash Games at Bety Casino
Blockchain technology increases the gaming offer for online casinos, providing games not supported by traditional casinos. For example, conventional casinos rely on the classic offer of vintage games with limited scalability and versatility potential. On the other hand, blockchain provides a fertile ground for boundless creativity, spurring innovative concepts, such as play-to-earn and hold-to-earn.Gaming diversity is one of the most exciting aspects of building a Web3 betting platform on blockchain technology. In addition to offering traditional casino games such as slots, poker, blackjack, and roulette, Web3 casinos also provide hash games.Hash games are fast-paced, simple games that mimic classic casino games while adding a pinch of excitement. The game mechanics use hash value calculation and blockchain algorithms to deliver a thrilling, straightforward gaming experience. Players must wager on a predicted hash interval and win if their prediction is correct. Hash games involve various betting options that broaden the winning odds.Bety has several hash games in its versatile blockchain gaming offer, including Hash Banker Player, Hash Bull, 3-Min Bull, 1-Min Banker Player, and more. These games function by simple, easy-to-understand rules and ensure provable fair outcomes with appealing RTP rates.
A Unique Classic Casino Gaming Offer
In the most recent offer upgrade, Bety reveals an enhanced gaming offer, including slots, live casino, table games, lottery games, and sports events. Users can pick from over 10,000 casino games from leading brands, such as PGSoft, Evolution Gaming, Evoplay, Yggdrasil, Red Tiger, EG Games, Spribe, JILI, AE Sexy, Ezugi, and PNG. This stellar collection of games from reputable brands ensures players have non-stop access to the latest games and live events while enjoying a cutting-edge gaming experience.Bety offers a versatile library of over 10,000 slot games from more than 100 leading brands. Many of these games involve highly appealing bonuses, making the playing experience even more exciting. The platform replicates an authentic casino experience through its live casino that players can enjoy without leaving their homes. Also, the table games section includes many traditional and fan-favorite games, such as poker, blackjack, baccarat, craps, roulette, and more.
Promotions & Bonuses
Bety also provides several promotions for new and veteran players to make the gaming experience even more thrilling and fulfilling. The platform offers bonuses on the first 4 deposits and 7-day and monthly bonuses. Furthermore, referring friends to Bety entitles players to additional bonuses and earning opportunities.
The VIP Program
Bety invites players to explore its large blockchain gaming selection. They can quickly make transparent and instant Bitcoin deposits to play these games and boost their profiles on the platform. In time, the most loyal players can enter Bety’s VIP program and enjoy several advantages, including cash back incentives, free chests, free spins, and personal VIP assistants. Moreover, the platform also supports instant Bitcoin withdrawals.
The post Bety Unveils Enhanced Offer of 20,000+ Crypto Games and Sportsbook Events appeared first on News, Events, Advertising Options.
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