HANOVER, N.H., March 25, 2025 /PRNewswire/ — Hubble Therapeutics LLC a patient-focused biotechnology company developing a gene therapy to cure pediatric blindness, announces the successful closing of a $7.3 million Series A funding round, which will advance its lead candidate, HUB-101, into human clinical trials.

Hubble Therapeutics’ gene therapy, HUB-101, targets two rare and devastating eye disorders: Leber Congenital Amaurosis (LCA16) and Snowflake Vitreoretinal Degeneration (SVD). This innovative treatment, developed by Dr. Bikash Pattnaik at the University of Wisconsin-Madison School of Medicine and Public Health and licensed from the Wisconsin Alumni Research Foundation (WARF), aims to address the root cause of these conditions. LCA16 and SVD are severe, early-onset retinal dystrophies caused by mutations in the KCNJ13 gene, which is crucial for the function of a vital ion channel in the retina’s pigment epithelium cells. These disorders typically manifest in children before the age of five, leading to progressive retinal degeneration over the following two decades and ultimately resulting in blindness.

“For over the past 20 years, my lab has developed in vitro and in vivo models of ion channelopathy to develop curative gene therapies for several devastating pediatric blindness diseases,” Dr. Bikash Pattnaik, professor in the Departments of Pediatrics, Ophthalmology and Visual Science at the University of Wisconsin–Madison, Daniel M. Albert Chair McPherson Eye Research Institute and scientific co-founder of Hubble Therapeutics LLC, “The development of the HUB-101 gene therapy for LCA16 represents not just the scientific breakthrough, but hope for patients and families affected by such devastating conditions caused by defective ion channels. As we push these therapeutic boundaries, we empower a future where innovative ion channel therapies in our lab address genetic diseases at their core.”

To date, HUB-101 has received Rare Pediatric Disease Designation and Orphan Disease Designation from the FDA for this program. It has partnered with Andelyn Biosciences in Columbus, Ohio, and Virscio in New Haven, Connecticut, to develop, manufacture, and conduct IND-enabling studies. Hubble Therapeutics expects to enter the clinic to conduct Phase I / II trials in 2026 to demonstrate the safety and efficacy of HUB-101.

“This groundbreaking research aims to restore vision in patients affected by a rare eye disease that ultimately results in complete blindness, with WARF’s investment in Hubble Therapeutics as the Series A co-lead investor, we are thrilled to continue our support for the development of a disease-modifying treatment,” says Greg Keenan, Senior Director of WARF Ventures & Accelerator and Hubble Therapeutics Board of Director. “The collaboration between Hubble Therapeutics and the pioneering research of UW-Madison inventor, Dr. Bikash Pattnaik, exemplifies the transformative potential of academic-industry partnerships and we are honored to continue our support in advancing this critical research alongside the dedicated team at Hubble Therapeutics.”

“We are grateful for our investors, leading scientists, industry experts, best-in-class partners, patient families, and the University of Wisconsin-Madison who share our commitment to realizing the promise of improving vision for patients suffering from LCA16 and SVD,” said Jeff Sabados, Founder and President of Hubble Therapeutics LLC. Sabados continued, “with our new financing and the establishment of key partnerships, we hope to scale up HUB-101 manufacturing and conduct additional IND-enabling studies to enter the clinic within the next two years to realize our steadfast, unwavering promise to support families throughout the world impacted by this devastating genetic disease.”

About Hubble Therapeutics, LLC
Hubble Therapeutics LLC (“HubbleTx”) is a patient-focused biotechnology company developing research from Professor Bikash Pattnaik’s lab at the University of Wisconsin-Madison. Our primary focus is on developing novel gene therapy for Leber Congenital Amaurosis Type 16 (LCA16) and Snowflake Vitreoretinal Degeneration (SVD), two debilitating retinal diseases that lead to severe vision loss in adult and pediatric patients. Our mission is to restore vision and improve the quality of life for affected individuals and their families by harnessing the power of gene delivery technology to target the underlying genetic mutation responsible for the disease. Our team of leading scientists, industry experts, and best-in-class partners are committed to rigorous research and clinical development, ensuring that our therapies are safe, effective, and accessible. HubbleTx strives to bring hope to those affected by this condition through collaboration and innovation. Together, we aim to illuminate the path to a brighter future for patients battling LCA16 and SVD.

For Hubble media inquiries, please contact:
jsabados@hubbletx.com

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DUBAI, UAE, March 25, 2025 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, is excited to announce the launch of Equity Trailing Stop, designed to empower traders with smarter risk control and profit protection. This intelligent tool allows users to trade with greater discipline by automating exit strategies, minimizing the potential risk of emotional pitfalls of trading.

The Equity Trailing Stop feature is available for Copy Trading Classic and is compatible with Spot Grid, Futures Grid, and Futures Combo bots, making it a versatile addition to any trading toolkit on Bybit’s one-stop trading platform.

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“The Equity Trailing Stop is a diligent and powerful co-pilot for traders who use automation and algorithm trading as part of their strategies. The new tool simplifies risk management, allowing Bybit users to stay disciplined and focused on their trading goals. This addition to our trading suite is part of our commitment to providing innovative solutions that enhance the trading experience,” said Joan Han, Sales and Marketing Director of Bybit.

To activate the feature, traders can set an Equity Trailing Stop percentage ranging from 5% to 99% when configuring Copy Trading parameters or creating a bot. This protective feature monitors positions and, once triggered, automatically closes any active Copy Trading positions or terminates running bots to help manage risk exposure. The Equity Trailing Stop operates by calculating exit equity through continuous updates based on the highest recorded equity in an account, ensuring the ability to capitalize on market movements while safeguarding investments.

Users may find out more at: Introducing Equity Trailing Stop: Smarter Risk Control & Profit Protection.

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Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving a global community of over 60 million users. Founded in 2018, Bybit is redefining openness in the decentralized world by creating a simpler, open and equal ecosystem for everyone. With a strong focus on Web3, Bybit partners strategically with leading blockchain protocols to provide robust infrastructure and drive on-chain innovation. Renowned for its secure custody, diverse marketplaces, intuitive user experience, and advanced blockchain tools, Bybit bridges the gap between TradFi and DeFi, empowering builders, creators, and enthusiasts to unlock the full potential of Web3. Discover the future of decentralized finance at Bybit.com.

For more details about Bybit, please visit Bybit Press
For media inquiries, please contact: media@bybit.com
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DELRAY BEACH, Fla., March 25, 2025 /PRNewswire/ — The Insurance Platform Market is slated to expand from USD 116.16 billion in 2025 to USD 207.52 billion by the year 2030 at an impressive CAGR of 12.3% over the forecast period, according to a new report by MarketsandMarkets™. 

Browse in-depth TOC on “Insurance Platform Market”

220 – Tables
72 – Figures
410 – Pages

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Scope of the Report

Report Metric	Details
Market size available for years	2020–2030
Base year considered Advertisement	2024
Forecast period	2025–2030
Forecast units	USD (Billion)
Segments Covered	Offering, Application, Technology, Insurance Type, End User, and Region
Geographies covered	North America, Europe, Asia Pacific, Middle East & Africa, and Latin America
Companies covered Advertisement	Salesforce (US), IBM (US), Microsoft (US), Google (US), Adobe (US), Oracle (US), SAP (Germany), Pegasystems (US), Accenture (Ireland), DXC Technology (US), Guidewire Software (US), Duck Creek Technologies (US), Applied Systems (US), Fineos (Ireland), Cognizant (US), Appian (US), Verisk (US), Bolttech (US), ServiceNow (US), LexisNexis (US), Majesco (US), EIS Group (US), Insurity Inc (US), Vertafore (US), Sapiens International Corporation (Israel), Prima Solutions (France), Cogitate Technology Solutions (US), AgencySmart (US), InsureSoft (Canada), BriteCore (US), Shift Technology (France), Zipari (US), Quantemplate (UK), Jenesis Software (US), Sureify (US), OneShield (US), Ensuredit (India), Socotra (US), Coalition (US), Symbo (India), TrustLayer (US), PerfectQuote (US), Hyperexponential (UK), InsuredMine (US), and InsuredHQ (New Zealand)

The rise of the Insurance Platform Market is being fueled by some key factors. One major driver is the wave of digital transformation sweeping across industries, prompting insurers to invest in advanced platforms that greatly enhance customer experiences, boost operational efficiency, and allow for data-driven decision-making. Additionally, the increasing demand for personalized insurance products—reflecting changing customer preferences—has encouraged the adoption of flexible and scalable solutions. The incorporation of artificial intelligence (AI), machine learning (ML), and data analytics has allowed insurers to offer dynamic pricing models, effective risk assessment tools, and automated claims processing. Regulatory shifts have also played a role, urging insurers to implement compliant platforms that come with top-notch security features. The influx of insurtech startups has further accelerated innovation and development in this area. With a focus on bettering customer engagement and streamlining their operations, investment in cloud-based and API-driven solutions is steadily increasing, marking significant growth in the Insurance Platform Market.

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By Application, the underwriting & risk management segment registers for the second-largest market share during the forecast period.

The underwriting and risk management application is expected to capture the second-largest share of the Insurance Platform Market due to its important role in evaluating risk, enhancing decision-making, and boosting operational efficiency. Cutting-edge insurance platforms that leverage AI, machine learning, and predictive analytics empower insurers to automate data analysis, leading to more accurate risk assessments. These innovative tools enable insurers to sift through massive amounts of data from diverse sources, including IoT devices, telematics, and customer profiles, ensuring that underwriting decisions are spot on. As insurers increasingly embrace data-driven approaches, platforms that provide advanced risk assessment models are becoming more popular. Moreover, the push for transparent risk evaluation processes due to regulatory requirements is prompting insurers to invest in strong underwriting solutions. The rising need for quicker policy issuance, fewer manual errors, and better fraud detection is also fueling the growth of underwriting and risk management solutions in the Insurance Platform Market.

By insurance type, specialty insurance is poised for the fastest growth rate during the forecast period.

The specialty insurance type is projected to be the fastest-growing segment in the Insurance Platform Market, fueled by an increasing need for custom coverage solutions in niche industries. Unlike traditional policies, specialty insurance covers unique risks such as cyber liability, marine and aviation risks, as well as high-value asset protection. As businesses venture into more complex markets and encounter evolving risks, insurers are turning to advanced platforms to create personalized solutions that cater to individual client needs. Digital platforms outfitted with data analytics, artificial intelligence (AI), and automation are enhancing risk assessment, pricing, and claims management for these specialized policies. Moreover, with the rise in cyber threats, environmental risks, and the complexities of global trade, the demand for specialty insurance is on the rise. Insurers are ramping up investments in flexible platforms that not only streamline underwriting processes but also improve customer interaction, further propelling the swift growth of the specialty insurance segment within the Insurance Platform Market.

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By Region, North America accounts for the largest market during forecast period.

North America is expected to maintain the largest market share within the Insurance Platform Market because of its sophisticated technological framework, high adoption rate of digital products, and prominent presence of well-established insurers. Insurers in the region are investing in new platforms to improve customer experience, simplify operations, and enhance risk assessment. Rising interest in data-driven insights, powered by the convergence of artificial intelligence (AI), machine learning (ML), and big data analytics, has further stimulated platform adoption. Moreover, the availability of a comprehensive regulatory framework makes insurers invest in compliant and secure digital technologies. Increasing usage of cloud-based platforms and API-based architectures is also driving the market’s growth. The rise of cloud-based platforms and API-driven architectures is also driving market growth. On top of that, North America’s vibrant insurtech ecosystem, marked by ongoing innovation and collaborations between traditional insurers and tech startups, is crucial in enhancing platform capabilities and reinforcing the region’s leadership in the Insurance Platform Market.

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Top Key Companies in Insurance Platform Market:

The major players in the Insurance Platform Market include Salesforce (US), Google (US), Adobe (US), Microsoft (US), Oracle (US), Guidewire Software (US), Duck Creek Technologies (US), IBM (US), Pegasystems (US), and Accenture (Ireland).

Browse Adjacent Markets: Software and Services Market Research Reports & Consulting

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About MarketsandMarkets™

MarketsandMarkets™ has been recognized as one of America’s Best Management Consulting Firms by Forbes, as per their recent report.

MarketsandMarkets™ is a blue ocean alternative in growth consulting and program management, leveraging a man-machine offering to drive supernormal growth for progressive organizations in the B2B space. With the widest lens on emerging technologies, we are proficient in co-creating supernormal growth for clients across the globe.

Today, 80% of Fortune 2000 companies rely on MarketsandMarkets, and 90 of the top 100 companies in each sector trust us to accelerate their revenue growth. With a global clientele of over 13,000 organizations, we help businesses thrive in a disruptive ecosystem.

The B2B economy is witnessing the emergence of $25 trillion in new revenue streams that are replacing existing ones within this decade. We work with clients on growth programs, helping them monetize this $25 trillion opportunity through our service lines – TAM Expansion, Go-to-Market (GTM) Strategy to Execution, Market Share Gain, Account Enablement, and Thought Leadership Marketing.

Built on the ‘GIVE Growth’ principle, we collaborate with several Forbes Global 2000 B2B companies to keep them future-ready. Our insights and strategies are powered by industry experts, cutting-edge AI, and our Market Intelligence Cloud, KnowledgeStore™, which integrates research and provides ecosystem-wide visibility into revenue shifts.

In addition, MarketsandMarkets SalesIQ enables sales teams to identify high-priority accounts and uncover hidden opportunities, helping them build more pipeline and win more deals with precision.

To find out more, visit www.MarketsandMarkets™.com or follow us on Twitter , LinkedIn and Facebook .

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