ST. PETERSBURG, Fla., Sept. 19, 2023 /PRNewswire/ — ARK Invest LLC (“ARK Invest” or “ARK”), the parent of ARK Investment Management LLC, the investment manager led by CEO Cathie Wood, has acquired Rize ETF Limited (“Rize ETF”), Europe’s first specialist thematic ETF issuer.
This transaction marks a significant milestone in ARK Invest’s global expansion strategy and will pave the way for the firm to introduce its suite of cutting-edge innovation ETFs, under the UCITS framework, to investors across Europe, the United Kingdom, and beyond, while also facilitating the sustained growth and expansion of Rize ETF’s thematic products.
“Today’s acquisition advances ARK Invest’s commitment to offer high-quality thematic investment solutions to a global investor audience, particularly European investors who have not been able to access our products,” said Cathie Wood, Founder, CIO, and CEO of ARK Invest. “We believe that the European ETF market presents a strong growth opportunity as new and younger investors continue to gain access to ETFs via the growth of digital platforms, and as active ETFs increase market share by meeting the demand for innovative investment exposures. We are delighted to welcome the talented Rize ETF team into the ARK family. By merging its passion for thematic and sustainable index investing with ARK’s innovative actively managed approach centered on disruptive innovation, we can offer our clients a more diverse array of investment options to invest in the future. Together, we will continue to educate and empower investors, helping them to achieve their long-term financial goals.”
Rize ETF is a leading European provider of thematic and sustainable investing. Founded in 2019 by thematic ETF pioneers Anthony Martin, Jason Kennard, Rahul Bhushan, and Stuart Forbes, Rize ETF specializes in creating high quality, research-led and purpose-built thematic ETFs. The Rize ETF Founders are a proven team of ETF experts and have over 40 years of combined ETF experience. They previously built the European ETF business for ETF Securities (acquired by WisdomTree) and Legal & General, respectively.
“The acquisition offers ARK an entry into the European ETF market, capitalizing on our expertise and track record in building multiple European ETF businesses,” said Stuart Forbes, Co-Founder of Rize ETF. “Leveraging ARK’s global network and our expertise in European distribution, we aim to strengthen our collective global presence. This initiative signifies not just business growth, but a collaborative exchange of global asset management best practices, insights, and tactics.”
The existing name and brand of Rize ETF will be phased out, and the platform will transition into “ARK Invest Europe,” which will be a division of ARK Invest Limited. ARK Invest Europe will serve as the hub for ARK’s expansion into the Europe, the UK and new markets globally. Under the new ARK Invest Europe platform, existing Rize ETF index products will remain available. ARK Invest Europe will continue to uphold the high standards of investment research, portfolio management, and client service for which ARK is known, all while tapping into Rize ETF’s deep expertise covering the full lifecycle of ETFs beginning with product strategy and index development, legal and regulatory, tax, portfolio management and operations, capital markets, research and marketing & distribution.
ARK purchased Rize ETF from AssetCo, a UK asset and wealth management business primarily involved in acquiring, managing, and operating asset and wealth management activities and interests, together with other related services. As part of this agreement, ARK and AssetCo will partner to support the launch, on the newly established ARK Invest Europe platform, of several ETF products for the River and Mercantile business, AssetCo’s active equity asset management subsidiary. ARK is minority-owned by Nikko Asset Management.
As of August 31, 2023, Rize ETF managed $452 million in assets in 11 ETFs all categorized as SFDR Article 8 or 9 compliant, domiciled in Dublin and distributed throughout Europe. ARK managed approximately $25 billion in ETFs and other products globally.
Additional details about the acquisition will be released in the coming weeks.
About ARK Investment Management LLC
ARK Investment Management LLC is a federally registered investment adviser and privately held investment firm. Specializing in thematic investing in disruptive innovation, the firm is rooted in over 40 years of experience in identifying and investing in innovations that should change the way the world works. Through its open research process, ARK identifies companies that it believes are leading and benefiting from cross-sector innovations such as robotics, energy storage, multiomic sequencing, artificial intelligence, and blockchain technology. ARK’s investment strategies include Autonomous Technology and Robotics, Next Generation Internet, Genomic Revolution, Fintech Innovation, Space Exploration & Innovation, 3D Printing, Israel Innovative Technology, Venture Capital, and the overall ARK Disruptive Innovation Strategy. For more information about ARK, its offerings, and original research, please visit www.ark-invest.com.
This document is for informational purposes only and does not constitute a general solicitation, offer or invitation in any funds or products in the United States or in any other jurisdiction and has not been prepared in connection with any such offer. The views expressed herein do not constitute investment or any other advice and are subject to change.
The Office of the Executive Committee of the WMC Released the List of “Top 500 Chinese Manufacturing Enterprises in 2023”
HEFEI, China, Sept. 22, 2023 /PRNewswire/ — The 2023 World Manufacturing Convention (WMC) was opened on September 20 in Hefei, Anhui Province, China. In the convention, the list of “Top 500 Chinese Manufacturing Enterprises in 2023” was released, indicating that the operating revenue of China’s top 500 manufacturing enterprises in 2023 has exceeded 50 trillion RMB for the first time, reaching 51.06 trillion RMB, which was an increase of 8.38%.
Among the top 500 manufacturing enterprises, the heavy chemical industry still occupies the main position, and four out of the five industries with the largest operating revenue belong to the heavy chemical industries. Meanwhile, the pace of development of strategic emerging industries has accelerated, and most of the enterprises with the top operating revenue and net profit growth are strategic emerging industry enterprises. The top five industry’s average revenue growth rates are from power batteries and energy storage batteries, wind energy, solar equipment manufacturing, medical equipment manufacturing, computer and office equipment and chemical fiber manufacturing, of which the top three growth rate reached more than 45%, respectively 59.72%, 49.42%, 45.54%. According to the analysis of the ranking, the total R&D expenses of China’s top 500 manufacturing enterprises in 2023 have reached 109.6215 billion RMB, which was an increase of 3.83% over the previous year; the R&D intensity was 2.33%, which is at a high level in recent years. The average R&D expenses of industries such as aerospace, communication equipment manufacturing, railway traffic equipment manufacturing, textile printing and dyeing are at the forefront from the perspective of various industries.
The “2023 Development Report on Anhui Manufacturing” prepared by the Anhui Provincial Department of Economy and Information Technology was also released on the day of the convention. The report shows that the average annual growth rate of industrial value added of enterprises above the designated size in Anhui Province was 9.5% from 2012 to 2022, ranking the first in the central region, the first in the Yangtze River Delta and the fourth in whole China. In 2022, the province’s industrial enterprises above the designated size have achieved an operating revenue of 4.9 trillion RMB, ranking 10th in the country. Among them, manufacturing enterprises above the designated size have achieved an operating revenue of 4.4 trillion RMB; the added value of the manufacturing industry has exceeded 1 trillion RMB, accounting for 26.5% of GDP, which was an increase of 0.3 percentage points over the previous year.
In recent years, Anhui’s manufacturing industry has accelerated the development of integrated clustering, especially the clustering of advanced manufacturing chains, forming an unformidable trend. The top one industry is “automobile” with irresistible force, while the PV and energy storage gathering “sparkling light” into a raging torch, the IC industry showing its brilliant “core”, the new “displays and screens” experiencing a rapid boom, and the AI “valley” astonishing the world. A number of industrial landmarks have become an important force leading the trend of China’s and even the world’s manufacturing industry.
Contact: Yuan Fan
Tel: 0086- 13552640063
E-mail: [email protected]
Asian International Arbitration Centre and SOAS University of London, Arbitration and Dispute Resolution Centre sign MoU to promote best practice in arbitration
LONDON, Sept. 22, 2023 /PRNewswire/ — The Asian International Arbitration Centre (AIAC), Kuala Lumpur, and SOAS University of London, Arbitration and Dispute Resolution Centre (SADRC) have yesterday (Thursday 21 September) signed a Memorandum of Understanding to advance collaboration and promote best practice in alternative dispute resolution techniques, including arbitration.
The MoU will see the AIAC and SADRC further develop teaching and research activities in alternative dispute resolution in line with international best practice, to coordinate efforts to promote the use of alternative dispute resolution.
Azalina Othman Said, Malaysia’s Minister of Law and Institutional Reform, was in London to attend the MoU signing, and offer it Malaysia’s full support to increase dialogue in arbitration. The Minister attend the MoU signing alongside Malaysia’s High Commissioner to the UK Dato’ Zakri Jaafar, Solicitor General II of the Attorney General’s Chambers of Malaysia, Datuk Almalena Sharmila binti Dato’ Dr. Johan, and Deputy Director General of the Legal Affairs Division of the Prime Minister’s Department, Dr. Punitha Silivarajoo. The Head of Legal Services Trade and Promotion at the UK Ministry of Justice, Holly O’Callaghan, attended to offer the UK Government’s support.
Speaking about the MoU signing, Emilia Onyema, Professor of International Commercial law, SOAS & Director, SADRC, said:
“At the SADRC, we are proud that today we have become a partner of the Asian International Arbitration Centre. Through signing this MoU, we hope to promote alternative dispute resolution techniques in our SOAS regions, Asia, Middle East and Africa, and particularly Malaysia, and learn from our shared experiences.”
Sundra Rajoo, Director of AIAC, said:
“We are delighted that today, the Asian International Arbitration Centre has formally agreed a MoU with SOAS University of London’s prestigious new Arbitration and Dispute Resolution Centre. The formalization of the MoU between both institutions is indeed a remarkable and significant achievement. We firmly believe that through this innovative partnership, we can enhance our joint efforts to promote best practices in alternative dispute resolution, benefiting not only the UK and Malaysia but also the broader Asian and African region.”
Azalina Othman Said, Malaysia’s Minister of Law and Institutional Reform, said:
”The UK and Malaysia have a long shared history of collaborating to tackle mutual challenges, and the signing of the MoU between the Asian International Arbitration Centre and SOAS University of London’s Arbitration and Dispute Resolution Centre underscores the depth of our relationship and our commitment to advancing global best practices in arbitration.”
In practical terms, this collaboration would include steps to encourage, enhance and promote the following areas of cooperation:
- Joint courses and training;
- Joint research programmes;
- Contribution of expertise – such as researchers, panellists, speakers and guest lecturers – to initiatives which share common goals;
- Publication of academic journals, books and newsletters;
- Student internship programmes;
- Organising or hosting joint conferences, workshops, seminars and forums.
In addition to arbitration, the two centres have committed to also promote Islamic arbitration, sports arbitration, mediation, adjudication, and domain name dispute resolution as alternative dispute resolution methods.
The MoU signing comes ahead of the inaugural London International Arbitration Colloquium, which will take place on Monday 25 September at the International Dispute Resolution Centre in London, to consider the role of international arbitration involving sovereign states.
Over the course of three panel sessions, guests will hear expert insights on jurisdictional challenges in investment arbitration, the impact of investment claims on states and their sovereignty, and the role of third-party funding in access to justice.
For more information, contact:
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Revolutionary Cancer Treatment Advances Promise Brighter Future Amid Federal Funding Uncertainty
FN Media Group Presents USA News Group News Commentary
VANCOUVER, British Columbia, Sept. 22, 2023 /PRNewswire/ — USA News Group – Despite the potential federal funding challenges due to the recent debt ceiling deal, optimism in the battle against cancer persists, thanks in large part to the audacious “Cancer Moonshot” initiative. This ambitious plan, aimed at halving cancer rates within the next quarter-century, continues to fuel hope even as concerns about the stability of National Institutes of Health (NIH) funding arise. In these turbulent times, the resilience and ingenuity of the biotech sector provide a beacon of hope. For instance, Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC), Zymeworks Inc. (NASDAQ: ZYME), Jazz Pharmaceuticals plc (NASDAQ: JAZZ), Protagonist Therapeutics, Inc. (NASDAQ: PTGX), and Amgen Inc. (NASDAQ: AMGN), have each demonstrated inspiring progress and unwavering commitment in advancing cancer treatments, highlighting their vital role in the future of cancer therapy.
At the 2023 ASCO Annual Meeting Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC) shared exciting results from its important study, called BRACELET-1, with results that caught the eye of RBC Capital. The oral presentation shared at the event described how they’ve been testing a treatment for advanced breast cancer, and it’s looking very promising.
The treatment combines Oncolytics’ flagship drug, pelareorep, with a well-known cancer medicine, paclitaxel. Pelareorep is a unique drug that targets and kills cancer cells by making them self-destruct while leaving healthy cells unharmed. The results of BRACELET-1 showed that this mixture could slow down the cancer significantly. It even lowered the risk of the cancer getting worse by a significant 71% compared to just using paclitaxel.
For people battling cancer, this means more quality time before the cancer might get worse. Specifically, people getting the combined treatment had about 9.5 good months before the disease advanced, compared to just 6.3 months with only paclitaxel.
Moreover, the new treatment was better at shrinking or even eliminating the cancer. An impressive 37.5% of patients responded to the combined treatment, as opposed to just 13.3% with paclitaxel alone.
“BRACELET-1’s positive results complement prior phase 2 data showing a statistically significant increase in overall survival when pelareorep was combined with paclitaxel by demonstrating similar robust improvements in PFS and ORR in less heavily pre-treated patients,” said Dr. Matt Coffey, President and CEO of Oncolytics Biotech. “Given this exciting finding, our next step is to discuss our data with the FDA to investigate incorporating dual PFS and OS endpoints into our breast cancer program’s registrational study. Including a PFS endpoint will substantially reduce the time to a pivotal readout from the registrational trial, thereby accelerating pelareorep’s path to potential approval as we work to address the urgent needs of HR+/HER2- breast cancer patients.”
Following these encouraging results, Oncolytics Biotech is now ready to take the next steps in advancing its breast cancer program. They’re planning to talk to the FDA and push forward with more registrational studies, having already received Fast Track Designation for pelareorep in the treatment of advanced/metastatic pancreatic cancer, in late 2022. This could make pelareorep an approved treatment for breast cancer sooner than expected.
Another highlight from the ASCO presentations was that of Jazz Pharmaceuticals plc (NASDAQ: JAZZ) and Zymeworks Inc. (NASDAQ: ZYME). Together the two companies presented promising data from a pivotal Phase 2b trial, evaluating the bispecific antibody, zanidatamab, in HER2-amplified biliary tract cancers (BTC), a particularly aggressive group of cancers that currently lack HER2-targeted treatment options.
The results were not only presented at ASCO but also concurrently published in The Lancet Oncology. They demonstrated meaningful clinical benefit, including antitumor activity, a confirmed objective response rate (cORR) of 41.3%, a median duration of response (DOR) of 12.9 months, and a median progression-free survival (PFS) of 5.5 months.
“The HERIZON-BTC-01 trial advances an exciting field of oncology research where we can leverage next-generation sequencing on BTC patients to understand genomic markers of the disease and choose the appropriate targeted therapies for these patients,” said Shubham Pant, M.D., professor of Gastrointestinal Medical Oncology and Investigational Cancer Therapeutics at The University of Texas MD Anderson Cancer Center.
The data clearly outshines current chemotherapy treatments for BTC, which offer only a 5 to 15 percent ORR and median PFS of 1.4 to 4 months. The Zymeworks-Jazz partnership showcased an oral presentation on the pivotal HERIZON-BTC-01 study results demonstrating zanidatamab’s meaningful clinical benefit and tolerable safety profile in patients with HER2-amplified BTC.
Zanidatamab has already been granted Breakthrough Therapy designation and two Fast Track designations by the FDA, making it an exciting contender in the fight against these tough-to-treat cancers. These exciting results suggest a potential future where targeted treatments like zanidatamab transform the lives of patients in critical need.
With three oral presentations and two poster discussions, and over 25 abstracts, Amgen’s (NASDAQ: AMGN) presence at ASCO included new scientific and clinical research across its diverse oncology portfolio and pipeline, featuring data in hard-to-treat tumor types like non-small cell lung cancer (NSCLC), colorectal cancer (CRC), and small cell lung cancer (SCLC).
“Our presentations at ASCO… illustrate how we’re advancing novel approaches to address the toughest thoracic and colorectal cancers with limited treatment options,” said David M. Reese, M.D., executive vice president of Research and Development at Amgen. “We’re focused on expanding the reach and impact of our transformative, first-in-class medicines to help more people living with cancer.”
Highlights from Amgen’s presentations included data on LUMAKRAS® (sotorasib) from the first study evaluating its intracranial efficacy as a KRAS G12C inhibitor versus docetaxel in treated KRAS G12C-mutated advanced NSCLC. Additional analyses from DeLLphi-300 highlighted the safety and clinical efficacy of Tarlatamab, an investigational first-in-class BiTE® immunotherapy, in patients with SCLC with treated and stable brain metastases. Other studies presented novel combinations showing encouraging safety and efficacy in pre-treated KRAS G12C-mutated metastatic CRC and first-line NSCLC.
These presentations showed advances in several therapeutic areas, including hematologic malignancies, melanoma/skin cancers, and gastrointestinal cancers. Some of the key clinical studies presented include the IKEMA study for KYPROLIS®, the PARADIGM trial for VECTIBIX®, and a phase 2 study on IMLYGIC® in advanced sarcoma.
One company also potentially (yet indirectly) making significant strides in the oncology sector is Protagonist Therapeutics, Inc. (NASDAQ: PTGX), a Newark, California-based biopharmaceutical firm. Although not traditionally labeled as a cancer biotech firm, their innovative approach towards blood disorders, notably Polycythemia Vera, a slow-growing blood cancer, underscores their contribution to the broader oncology landscape.
Protagonist’s leading drug candidate, rusfertide (PTG-300), is currently under the microscope. The company recently announced that additional data from the REVIVE study of rusfertide in polycythemia vera would be presented at the annual Congress of the European Hematology Association (EHA). This study holds immense promise as it explores the ability of rusfertide to improve symptoms related to this blood disorder.
The Moffitt Cancer Center and the Department of Malignant Hematology have taken a keen interest in this study, suggesting rusfertide’s potential broader application in the field of hematology and possibly in other forms of cancer. An assistant member of the Department, Dr. Andrew Kuykendall, will present the study results, further demonstrating the deep links between Protagonist’s work and oncology professionals.
Moreover, Protagonist is also advancing their peptide-based new chemical entity, JNJ-2113 (formerly PN-235), which recently showed positive topline results in treating moderate-to-severe plaque psoriasis. While psoriasis is not a form of cancer, the advancement of these biological drugs signals a new direction in treating various human conditions, including cancers.
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- The Office of the Executive Committee of the WMC Released the List of “Top 500 Chinese Manufacturing Enterprises in 2023”
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