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Pancreatic Cancer Research Gains Momentum Amidst Soaring Young-Onset Cases
FN Media Group Presents USA News Group News Commentary
VANCOUVER, British Columbia, Sept. 26, 2023 /PRNewswire/ — USA News Group – The seriousness of pancreatic cancer continues to grow, with increasing alarm since The Lancet published an analysis back in April 2023, showing a rising incidence of pancreatic cancer among individuals younger than 55 years. Another study published in JAMA Network Open showed that early-onset cancer in people younger than 50 rose over the last decade, with gastrointestinal cancers seeing the fastest increase. This has led to increased calls from pancreatic cancer organizations such as Pancreatic Cancer Action Network (PanCAN) for more action in the space, including advocating that the US Congress invest more in cancer research funding now. Among the ongoing efforts that are drawing more attention in the pancreatic cancer space have been the developments coming from Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC), Merus N.V. (NASDAQ: MRUS), Guardant Health, Inc. (NASDAQ: GH), Medtronic plc (NYSE: MDT), and even NVIDIA Corporation (NASDAQ: NVDA).
PanCAN recently followed up their selection of pelareorep—the leading drug candidate of Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC)—for their pivotal Phase 3 trial, by rewarding the drug’s developer with its second annual PanCAN Therapeutic Accelerator Award. The award comes with a US$5 million grant to further develop leading-edge treatments.
For Oncolytics Biotech, the grant will enable the company to continue the next stage of its research focused on a clinical trial with pelareorep, this time in combination with modified FOLFIRINOX chemotherapy with or without an immune checkpoint inhibitor.
“This generous grant will enable early and late-stage patients with pancreatic cancer to potentially benefit from another commonly employed chemotherapy backbone, as FOLFIRINOX and gemcitabine + nab-paclitaxel are the most frequently used chemotherapy standards of care in both the first and second-line setting,” said Dr. Matt Coffey, President and CEO of Oncolytics Biotech. “By teaming up with PanCAN, we believe we may be able to expedite development and provide pancreatic cancer patients with a bespoke immunotherapeutic treatment option.”
Prior to the award, ONCY successfully raised another US$15 million to continue the advancement of its pelareorep clinical programs in both pancreatic and metastatic breast cancers, with the significant support from an institutional investor. With the injection of another US$5 million from the PanCAN grant, Oncolytics is in an excellent cash runway position. According to their Q2 2023 financial results, on a pro forma basis, including the net proceeds from the public offering, Oncolytics had CAD$42.7 million on June 30, 2023, which should last them into the second half of 2024.
“Our core programs in pancreatic and breast cancer are both progressing rapidly towards registrational studies on the back of the impressive clinical data showing the potential of pelareorep as a backbone immunotherapy,” said Dr. Coffey. Pelareorep delivered the company a big win near the end of 2022, when the FDA rewarded it with a Fast Track Designation (FTD) for treating advanced or metastatic pancreatic cancer. This came right after an update on ONCY‘s GOBLET study, which delivered amazing results, including a 69% objective response rate (ORR) in the first group of patients tested and one even having a rare complete response (CR).
“With a five-year survival rate of 12%, pancreatic cancer patients cannot afford to wait for new treatment options,” said Julie Fleshman, JD, MBA, President and CEO of PanCAN. “This urgent unmet need was the driving inspiration behind the Precision Promise platform trial, which was designed specifically to identify, accelerate, and de-risk the development of promising pancreatic cancer treatments. We are thrilled to be bringing pelareorep into Precision Promise as a new investigational therapy to study against the current standard of care.”
Another pancreatic cancer therapy that received a boost from the FDA was Merus N.V. (NASDAQ: MRUS), which, back in early July 2023, received a Breakthrough Therapy Designation for its drug Zeno (zenocutuzumab) for the treatment of patients with advanced, unresectable or metastatic NRG1 fusion pancreatic cancer that has gotten worse with a prior systemic therapy and has no other satisfactory treatment options.
“We believe the compelling clinical data for Zeno in NRG1-positive cancer, and Breakthrough Therapy Designation, provide the opportunity to further engage with the FDA to expedite the review of a potential (Biologics License Application) submission,” said Dr. Bill Lundberg, President and CEO of Merus.
Based on information provided during the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, it was found that 34% of patients who underwent treatment with Zeno witnessed a positive response. This response indicated a reduction in tumor size or complete disappearance, with an average response duration of 9.1 months. This data compilation involved 79 patients who were diagnosed with various solid cancers, all of whom had an NRG1 fusion.
At the 2023 ASCO GI Annual Meeting there was a demonstration by Guardant Health, Inc. (NASDAQ: GH) of its blood tests for patients with gastrointestinal cancers. Spanning over 10 poster presentations, Guardant shared important updates of its Guardant360® and Guardant Reveal™ blood tests, as well as the GuardantINFORM™ real-world evidence dataset to identify critical biomarkers and acquired co-mutations, track associated treatment patterns and clinical outcomes, and predict disease recurrence from minimal residual disease (MRD) detection.
The Guardant360 CDx test was the first blood test to be approved by the FDA for comprehensive genomic profiling for all solid tumors, and it is now FDA-approved as a companion diagnostic test for four targeted therapies in NSCLC and one in advanced breast cancer.
While Guardant‘s blood tests are making progress, endoscopic ultrasound (EUS) is still considered one of the most useful imaging studies for diagnosing pancreatic cancer, and the technology behind endoscopies is also rapidly progressing.
Back in March, Medtronic plc (NYSE: MDT) announced a plan with Cosmo Pharmaceuticals NV and NVIDIA Corporation (NASDAQ: NVDA) to integrate Nvidia‘s artificial intelligence technologies into Medtronic’s GI Genius intelligent endoscopy module—the first FDA-cleared, AI-assisted colonoscopy tool to help physicians detect polyps that can lead to colorectal cancer.
“The possibility for GI Genius to host multiple real-time AI applications is a game-changer for physicians performing gastrointestinal procedures,” said Giovanni Di Napoli, president of the Gastrointestinal business at Medtronic. “With the launch of our AI Access™ platform, we are now able to support developers everywhere and accelerate the creation of real-time AI applications. This technology may allow us to offer clinicians expanded access to these tools, potentially improving patient outcomes. We believe that the AI Access platform may be a critical tool for advancing medical AI innovation and improving patient care in the years to come.”
Article Source: https://usanewsgroup.com/2023/05/31/could-this-company-be-on-track-to-cure-pancreatic-and-breast-cancer-2/
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Fintech PR
EQT to acquire Indostar Home Finance, an Indian affordable housing finance company, for INR 17.5 billion (USD 210 million) and invest INR 5 billion to support further growth
STOCKHOLM, Sept. 19, 2024 /PRNewswire/ —
- Indostar Home Finance is a fast-growing affordable housing finance company with INR 24 billion (USD 286 million) in assets under management, that has supported over 39,000 low income homeowners and small businesses
- India’s INR 30 trillion housing finance market presents a multi-decade growth story driven by strong government support, rising affordability and urbanization
- EQT will invest INR 5 billion in primary capital to support Indostar Home’s continued growth, including by broadening its footprint across India and investing in digital capabilities
EQT is pleased to announce that the BPEA Mid-Market Growth Partnership (or “the MMG fund”) has agreed to acquire a 100% stake in Indostar Home Finance (or “the Company”), a wholly owned subsidiary of Indostar Capital Finance Limited, for INR 17.5 billion (USD 210 million).
Founded in 2017, Indostar Home Finance provides affordable mortgages to retail customers in tier 2 to tier 4 cities in India and has supported over 39,000 low income homeowners and small businesses. The Company has rapidly scaled to more than INR 24 billion in assets under management, achieving a 32 percent compounded annual growth in the last three years. Indostar Home Finance has a network of more than 130 branches spread across nine states and employs over 1,000 people.
The Indian housing finance market currently stands at more than INR 30 trillion, according to the CRISIL. The segment has recorded strong growth driven by government support, rising affordability, and urbanization. However, there remains a significant shortage of housing in the country, with India’s mortgage to GDP ratio at 12.3% compared to more than 60% for developed countries like the USA and UK.
The MMG fund will invest INR 5 billion of primary capital in Indostar Home Finance to support its next phase of growth. EQT aims to expand the Company’s geographic footprint and accelerate its digital transformation journey by leveraging EQT’s in-house digitalization expertise, network of seasoned industry advisors, and expertise in go-to-market strategies.
Ashish Agrawal, Partner in the EQT Private Capital Asia advisory team, said: “Retail lending is a key investment theme for EQT within financial services in India. Building on our investment in the education finance sector through HDFC Credila last year, we are thrilled to welcome Indostar Home Finance to our portfolio. India’s affordable housing finance sector represents a long-term growth opportunity supported by secular demand drivers, favorable government policies and resilient asset quality across economic cycles”
Hemant Sharma, Managing Director in the EQT Private Capital Asia advisory team, said: “Indostar Home Finance has established itself as a leading player in this segment and is well-positioned for continued growth. We are impressed by its market-leading position in South India and strong underwriting capabilities. We see significant potential to expand Indostar’s presence across India and drive its digital transformation. EQT looks forward to supporting the company in its next phase of growth.”
Mr. Shreejit Menon, CEO of Indostar Home Finance, said: “This transaction marks a key milestone for Indostar Home Finance. We are excited to embark on this new journey with EQT, who shares our vision and whose partnership will significantly help advance our mission of delivering affordable housing finance solutions across India. With EQT’s support and global expertise, we are well-positioned for accelerated growth and success.”
The transaction is subject to customary regulatory approvals.
Contact
EQT Press Office, [email protected]
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LYON, France, Sept. 19, 2024 /PRNewswire/ — After an intense week of competition, the 47th WorldSkills Competition has officially wrapped up, marking the end of a thrilling journey for 1,400 young professionals from around the globe. For four days, participants representing nearly 70 countries and regions competed fiercely in 59 diverse skill areas, transforming Lyon’s Eurexpo into a vibrant hub of craftsmanship and international talent.
From day one, the atmosphere was charged with energy as competitors showcased their expertise in sectors ranging from Manufacturing and Engineering to Fashion, Digital Technology, and Healthcare. The level of dedication and precision demonstrated throughout the week was a testament to the profound commitment these young professionals have to their trades, as well as their determination to showcase their nation’s worth on the global stage.
Last night, the closing ceremony of WorldSkills Lyon 2024, held at Groupama Stadium, brought the event to an emotional close with the announcement of medalists in each skill category. Four medals were awarded in each skill: Gold Medal, Silver Medal, Bronze Medal, and the Medallion for Excellence. This ceremony underscored the core belief of the WorldSkills movement: excellence is found in diversity – diversity of profiles, backgrounds, expertise, and techniques.
The list of medalists is now available. Visit https://worldskills.org/what/competitions/worldskills-lyon-2024/#results to discover the winners!
What’s next?
The impact of WorldSkills Lyon 2024 extends far beyond the event itself. As the competition unfolded, and millions of people followed it in person or through media, WorldSkills Lyon 2024 spotlighted the crucial role of vocational education in today’s world and in shaping our shared future. By celebrating excellence, the competition highlighted the incredible ability of youth to drive the change our world needs through their energy and dedication. The legacy of this event lies in every vocation it has sparked and every future career it has inspired. This 47th edition has once again shown the world that where there is skill, there is a way.
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Fintech PR
Touchless Vending Market Size to Grow USD 42330 Million by 2030 at a CAGR of 13.3% | Valuates Reports
BANGALORE, India, Sept. 19, 2024 /PRNewswire/ — Touchless Vending Market is Segmented by Type (Food and Beverage Vending Machines, Mask Vending Machine, Toy Vending Machine), by Application (Shopping Mall, Street, Hospital, Traffic Station): Global Opportunity Analysis and Industry Forecast, 2024-2030.
The Global Touchless Vending Market was valued at USD 19800 Million in 2023 and is anticipated to reach USD 42330 Million by 2030, witnessing a CAGR of 13.3% during the forecast period 2024-2030.
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Major Factors Driving the Growth of Touchless Vending Market:
The touchless vending machines market is seeing rapid growth, driven by rising demand for hygienic, contactless solutions post-pandemic, especially in public places such as shopping malls, traffic stations, and hospitals. The ability to offer convenience and reduce human interaction has made these machines popular in food and beverage, personal protective equipment (PPE), and even toy vending. Technological advancements in contactless payment systems and smart inventory management further boost adoption. However, high initial investment costs may slow market growth, especially in developing regions.
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TRENDS INFLUENCING THE GROWTH OF THE GLOBAL TOUCHLESS VENDING MARKET:
Food and beverage vending machines are highly popular in locations such as hospitals, shopping malls, and traffic stations, where consumers demand quick, hygienic access to snacks and drinks. These machines, equipped with touchless payment systems, Employee Background Check Software Market have seen increased adoption due to the convenience and enhanced hygiene they offer. In addition to traditional snacks and drinks, there is a growing trend toward healthier, premium food options in these vending machines, catering to health-conscious consumers, which further drives demand in this segment.
In shopping malls, vending machines are increasingly being used to provide convenience to shoppers, offering products ranging from snacks to toys and hygiene products. Touchless vending machines are particularly appealing due to their ability to cater to consumers who are looking for quick, contactless purchasing options while shopping. The presence of vending machines in high-traffic areas within malls ensures steady usage, and as malls look to enhance customer experiences, more advanced, interactive vending solutions are likely to be adopted.
Mask vending machines gained significant traction during the COVID-19 pandemic and continue to be relevant in hospitals, airports, and other high-traffic areas. These machines offer a convenient, touchless way for people to access face masks and personal protective equipment. While demand for masks has decreased slightly post-pandemic, the continued emphasis on public health and hygiene in high-risk locations ensures that these machines maintain a stable presence. Additionally, mask vending machines are being repurposed for other hygiene products, extending their utility.
Toy vending machines are commonly seen in shopping malls and entertainment centers, offering children and families a fun, convenient way to purchase toys. These machines are especially popular in high-traffic areas such as malls and family-friendly environments, where they offer an added entertainment element. Recent trends show a shift toward integrating digital elements, such as mobile apps and touchless payment options, into toy vending machines, enhancing the user experience and making these machines more interactive and appealing to younger audiences.
In hospitals, vending machines play a crucial role in providing essential items like snacks, beverages, and personal protective equipment (PPE), including masks. Touchless vending machines, in particular, have become more popular in healthcare environments due to their ability to reduce physical contact, thereby minimizing the risk of disease transmission. These machines are strategically placed in high-traffic areas, such as waiting rooms and cafeterias, ensuring that both staff and visitors have easy access to essential items without leaving the hospital premises.
Vending machines in traffic stations, including airports, bus terminals, and train stations, are seeing increased demand as more travelers seek convenient, contactless solutions for snacks and beverages during transit. Touchless vending machines are particularly favored in these locations due to their ability to offer quick, hygienic services to large numbers of travelers. With the growing number of people using public transportation, vending machines equipped with smart technology and contactless payment options are expected to become a staple in these locations.
Touchless vending machines are also becoming a common sight on streets and in other public spaces, providing convenience for passersby. These machines offer quick access to a variety of products, including food, beverages, and even hygiene items, such as masks and sanitizers. The convenience of contactless payment and minimal human interaction aligns well with the growing consumer preference for self-service, especially in outdoor environments. The installation of vending machines in streets and public spaces is expected to continue rising, driven by urbanization and consumer demand for 24/7 access to essential goods.
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TOUCHLESS VENDING MARKET SHARE
The Asia-Pacific region dominates the touchless vending machines market, driven by the high adoption rate of vending machines in countries like Japan and China, particularly in public spaces such as traffic stations and shopping malls. North America and Europe also show strong demand, especially for food and beverage vending machines in hospitals and other high-traffic areas. The Middle East and Africa are emerging markets, with increasing investments in smart city infrastructure and public health initiatives that support the adoption of touchless vending machines.
Key Companies:
- Digital Media Vending International LLC
- AusVendGroup
- AMS Group, Inc.
- LuxDisinfect
- Aeguana
- Vendekin
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DISCOVER MORE INSIGHTS: EXPLORE SIMILAR REPORTS!
– Contactless Touch Technology market was valued at USD 986.4 Million in 2023 and is anticipated to reach USD 1422.1 Million by 2030, witnessing a CAGR of 5.4% during the forecast period 2024-2030.
– AI-Powered Checkout market was valued at USD 217 Million in 2023 and is anticipated to reach USD 681.6 Million by 2030, witnessing a CAGR of 17.5% during the forecast period 2024-2030.
– Hospital Vending Machine Market
– Capsule-Toy Vending Machines market is projected to grow from USD 351 Million in 2024 to USD 635.8 Million by 2030, at a Compound Annual Growth Rate (CAGR) of 10.4% during the forecast period.
– The global Digital Process Automation market is projected to grow from USD 7215.7 Million in 2024 to USD 11770 Million by 2030, at a Compound Annual Growth Rate (CAGR) of 8.5% during the forecast period.
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