Fintech PR

GLP-1: Beyond Diabetes, a Blockbuster Horizon Beckons

Published

9 months ago

January 10, 2024

NetworkNewsWire Editorial Coverage

NEW YORK, Jan. 10, 2024 /PRNewswire/ — On Sept. 20, 2019, history was made when the U.S. Food and Drug Administration approved Rybelsus as the first oral glucagon-like peptide-1 (GLP-1) agonist for type 2 diabetes (T2D). However, it wasn’t just a milestone for T2D management. It was a turning point in medicine, opening the floodgates to a universe of potential therapeutic applications for this remarkable molecule. While undeniably transformative for diabetes and weight loss, GLP-1’s reach now extends far beyond, likely surpassing even the wildest dreams of its creators. From Alzheimer’s and Parkinson’s to drug addiction, clinical trials are painting a stunning picture of GLP-1’s versatility. And it doesn’t stop there. Strong evidence points to opportunities in heart disease, chronic kidney disease and a plethora of other conditions. The newfound applications of this super-drug re-enforce the significant potential for Lexaria Bioscience Corp. (NASDAQ: LEXX) (Profile), with its powerful DehydraTECH(TM) drug-delivery formulation and processing technology that improves both delivery and efficacy of GLP-1 for diabetes and potentially a host of other maladies. Lexaria joins other companies, including Amgen Inc. (NASDAQ: AMGN), Eli Lilly and Company (NYSE: LLY), Roche (OTCQX: RHHBY) and WW International Inc. (NASDAQ: WW), that are committed to providing powerhouse solutions in the fields of diabetes, weight loss and more.

GLP-1 agonists are among the hottest drugs in healthcare, with uses targeting multibillion-dollar diabetes and obesity markets and much more.
Lexaria Bioscience has developed DehydraTECH drug-delivery platform, which is being shown to improve pharmacokinetics of orally administered drugs.
A pilot study evaluated a dose of the GLP-1 drug Rybelsus to one processed with DehydraTECH, showing Lexaria’s tech improves the safety and efficacy of the drug.
Lexaria issued final data from the pilot study and is planning for multiple human and animal studies early in 2024.

Click here to view the custom infographic of the Lexaria Bioscience Corp. editorial.

Diabetes and Obesity: A Growing Concern with a Glimmer of Hope

Imagine a silent storm raging inside countless bodies, a chronic battle against rising blood sugar. This is the reality for the 422 million people worldwide battling diabetes, a disease with tentacles that reach far beyond elevated glucose levels. Uncontrolled blood sugar dramatically increases the risk of devastating comorbidities, including kidney disease, vision loss, amputations, heart attacks, strokes and early death.

The storm often gathers strength in the wake of another global health crisis: obesity. Data paints a disturbing picture — 41.9% of U.S. adults now obese, with the worldwide number ballooning to 1.9 billion in 2016 from about 650 million in 1975. This unholy alliance of diabetes and obesity affects a staggering 25% of the world and exacts a heavy toll, not just on health but also on the economy. A conservative estimate puts the global economic burden at more than $2 trillion.

Amid the storm clouds, a glimmer of hope emerges. Enter GLP-1 agonists as a new frontline defense. These drugs mimic a natural gut hormone, prompting the body to produce insulin, regulate blood sugar and even suppress appetite. They’re proving to be powerful weapons in the fight against both diabetes and obesity, offering a chance for a diabetes patient to reclaim control of their blood sugar.

The rising rate of diabetes and obesity diagnoses is creating unprecedented demand for innovative treatments. In 2022, the global diabetes drug market alone surged to $61.87 billion, a figure that pales in comparison to the projected tsunami of spending reaching ~$118 billion by 2032. Scientists are counting on GLP-1 drugs to fight obesity too, another market figured to also top $100 billion in the next decade.

GLP-1 agonists, already blockbusters for diabetes and obesity, are just getting going. That’s the potential Lexaria Bioscience Corp. (NASDAQ: LEXX) unlocks with its DehydraTECH platform. The DehydraTECH solution is designed to enhance drug delivery and efficacy, not only orally but even into the brain for centrally acting compounds. Consider bypassing injections and unlocking new treatment possibilities — that’s DehydraTECH’s revolutionary promise. With proven benefits for oral medications and potential for dissolvable oral applications, Lexaria positions itself at the forefront of maximizing the impact of these life-changing drugs.

Lexaria is initially focused on diabetes and obesity as the low-hanging fruit, but the company isn’t just tackling these indications with its DehydraTECH platform; it’s aiming for a whole menu of medical victories. This disruptive drug-delivery tech boasts faster, better absorption into both bloodstream and brain, making it applicable for conditions such as oral nicotine (where rapid delivery could be a major benefit). This isn’t simply hyperbole. Lexaria recently announced its first human GLP-1 study, with compelling results fueling excitement for a future where DehydraTECH supercharges the molecule’s effect. While diabetes and obesity are tremendous market opportunities, Lexaria is thinking bigger as a platter of medical hope.

DehydraTECH + Rybelsus(TM)

Lexaria Bioscience is aiming to plant its flag in the GLP-1 agonist space with its DehydraTECH platform. After early animal studies hinted at DehydraTECH’s blood-sugar-lowering abilities, the company’s first human test has impressed. DehydraTECH-powered Rybelsus(TM) (oral semaglutide), a blockbuster diabetes drug, lowered blood glucose levels much better than the original alone, possibly thanks to its superior delivery punch to deliver more of the GLP-1 drug into human bloodstream than did Rybelsus itself. It’s early in the game, but Lexaria commands attention to possibly improve the standard of care with a supercharged GLP-1 agonist.

Rybelsus is a top-selling drug in the diabetes market, posting sales of ~$1.63 billion in 2022 and recording $1.234 billion in sales during just the first half of 2023. Moreover, Ozempic, a weekly injectable semaglutide, registered sales of $6.174 billion in the first half of 2023. Recent studies by Lexaria show their platform boosts Rybelsus’ blood-sugar-bludgeoning power, which certainly opens discussions about the potential. The stakes are high to find the most efficacious oral medication considering that injections are a pain point for patients.

The research, conducted by a university researcher, completed a head-to-head comparison of Rybelsus alone versus DehydraTECH-formulated Rybelsus. Compared to a single dose of standard Rybelsus, DehydraTECH-powered Rybelsus showed sustained higher drug levels, quicker peak delivery, superior blood sugar control and even fewer side effects. The seven-participant study hints at a future where oral diabetes drugs could pack a much bigger punch, potentially giving injections a run for their money.

The data speaks volumes. At 24-hours post administration, blood-sugar levels in patients treated with Rybelsus were unchanged from baseline, while those in the DehydraTECH group experienced a 5.01% reduction, a significant improvement. Further, while the control group’s glucose soared 21.7% after a meal, DehydraTECH kept that number locked down to a mere 6.2%, showcasing its superior blood sugar control.

Besting a $1.8 Billion Technology

Armed with this data, Lexaria’s is moving forward with a purpose to validate and capitalize on its initial DehydraTECH results. The company is fast-tracking larger trials to confirm the improved efficacy and safety shown in the most recent research while its focus is firmly fixed on a commercial partnership.

Moving forward, Lexaria is planning to initiate multiple studies further proving the prowess of DehydraTECH. For starters, the company will conduct additional human pilot studies in the next several months to examine another GLP-1 drug as well as evaluate a swallow-free oral dissolvable. It will also launch a multiweek animal pharmacokinetic and efficacy trial to optimize DehydraTECH for weight loss and other performance metrics. Elsewhere, the company is in the planning stages for a long-term stability test program for the purpose of determining if DehydraTECH-formulated GLP-1 drugs can go unrefrigerated during storage, unlike today’s injectable GLP-1 drugs, a factor that will reduce cost and increase logistic simplicity.

Beginning in the April–June quarter, Lexaria has intentions to study DehydraTECH-GLP-1 in a multiweek chronic human trial. In this study, the company will gain insight in both diabetes-related control (in part via reduced blood sugar levels) as well as weight loss and side effects.

Predicting the DehydraTECH impact on the GLP-1 market is a difficult task at this point. The company is rapidly building a data set with the hopes of sealing a deal with an interested pharmaceutical giant. With whispers of efficacy multiplying and side effects diminishing, the potential to disrupt a multibillion-dollar market is, arguably, an achievable target.

To put this into perspective, understand that the last time a drug-delivery technology achieved such an improvement, Novo Nordisk agreed to pay $1.8 billion to acquire Emisphere’s SNAC technology, subsequently putting the technology into Rybelsus tablets. That bears repeating, considering the $1.8 billion technology currently embedded in Rybelsus tablets was just outperformed by DehydraTECH technology.

Proving More Differentiation

GLP-1 drugs are undoubtedly popular due to their efficacy and intriguing safety profile compared to other drugs for the same indications, but they are still far from perfect. Their side effects include diarrhea, vomiting, nausea and more. Plus, they are still somewhat new, so long-term research is ongoing to evaluate delayed effects that could be related to bone density and muscle loss. To wit, DehydraTECH improving pharmacokinetics to reduce side effects can be instrumental in gaining market share in the future.

In the pilot study, DehydraTECH impresses on this front. None of the participants treated with DehydraTECH-formulated Rybelsus experienced any moderate or severe nausea or diarrhea. Conversely, those receiving the Rybelsus control tablets dealt with moderate nausea and diarrhea.

Lexaria isn’t just about blockbuster potential, it’s about smart business. DehydraTECH delivers a double whammy: lower costs for pharma giants and higher demand from patients seeking better delivery and efficacy. And to lock this golden goose in, the company has built a fortress of patents – 38 already granted and counting across the globe.

Only the Beginning

With each new study, the horizon of GLP-1’s therapeutic potential expands, painting a vibrant picture of a future where a single molecule could tackle a multitude of human afflictions, including neurological disorders (e.g., Alzheimer’s and Parkinson’s), cardiovascular conditions (e.g., heart disease, high blood pressure, atherosclerotic plaques, inflammation), cancer, autoimmune disease (e.g., Crohn’s), and many new possibilities. Additional companies and studies are investigating the efficacy of GLP-1 drugs on kidney disease, liver disease, bone health and even aging.

Amgen Inc. (NASDAQ: AMGN) is developing Maridebart cafraglutide (formerly AMG 133), or Mari for short. Mari is a gastric inhibitory polypeptide receptor (GIPR) antagonist and GLP-1 receptor agonist. It is being investigated in a phase 2 trial for the treatment of obesity with more than 640 patients, with and without diabetes, enrolled in the study.

Eli Lilly and Company (NYSE: LLY) recently announced that the U.S. Food and Drug Administration had approved its Zepbound(TM) (tirzepatide) for chronic weight management, a powerful new option for the treatment of obesity or overweight with weight-related medical problems. Adults taking Zepbound in a clinical trial lost on average 48 pounds at the highest dose. Zepbound is the first and only approved treatment activating two incretin hormone receptors, GIP and GLP-1, to tackle an underlying cause of excess weight.

Roche (OTCQX: RHHBY) announced last month that it had entered into a definitive merger agreement to acquire Carmot Therapeutics Inc., a privately owned U.S. company based in California. Carmot’s R&D portfolio includes clinical-stage subcutaneous and oral incretins with best-in-class potential to treat obesity in patients with and without diabetes, as well as a number of preclinical programs. The announcement noted that existing clinical data for Carmot’s assets, especially the lead asset CT-388, suggests potential to achieve and maintain weight loss with differentiated efficacy.

WW International Inc. (NASDAQ: WW) last month launched a new behavior-change program designed to support the unique needs of individuals on GLP-1 medications. The WeightWatchers GLP-1 Program was developed by a team of obesity specialists, clinicians, behavior-change scientists, dietitians and fitness experts to solve a gap in the market as members navigate life on new weight-loss medications.

GLP-1 has transcended its initial promise — its story is now a thrilling saga of scientific exploration and medical triumph. The implications are vast, not only for the millions struggling with diverse ailments but for the future of medicine itself. This is just the beginning. The curtain has risen on a new era, where GLP-1, the once-humble diabetes drug, stands poised to rewrite the script for countless medical journeys.

For more information about Lexaria Bioscience Corp., please visit Lexaria Bioscience Corp.

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Fintech PR

Enabling Regenerative Agriculture for Independent Smallholders in Indonesia: The BIPOSC Project, in Collaboration with Musim Mas, L3F, SNV Indonesia, and ICRAF

Published

10 mins ago

October 18, 2024

CISION (PR Newswire)

enabling-regenerative-agriculture-for-independent-smallholders-in-indonesia:-the-biposc-project,-in-collaboration-with-musim-mas,-l3f,-snv-indonesia,-and-icraf

JAKARTA, Indonesia, Oct. 18, 2024 /PRNewswire/ — Musim Mas Group, the Livelihoods Fund for Family Farming (L3F), SNV Indonesia, and World Agroforestry (ICRAF) are collaborating to improve the knowledge and capacity of independent oil palm smallholders through the Biodiverse & Inclusive Palm Oil Supply Chain (BIPOSC) project.

The project began in 2021 and takes a long-term approach to sustain a deforestation-free supply chain, regenerate degraded land, restore local biodiversity, and improve the livelihoods of independent smallholder farmers in Labuhanbatu, North Sumatra. BIPOSC will achieve this through implementing regenerative agriculture, locally adapted agroforestry models, capacity-building for sustainable businesses, and others.

The independent palm smallholders taking part previously received complementary training from Musim Mas. Following the training, these smallholders formed a smallholder’s association, Labuhanbatu Independent Oil Palm Smallholders Association (APSKS LB), North Sumatra. Musim Mas encourages smallholders to form associations to get better access to resources and obtain certification by the Roundtable on Sustainable Palm Oil (RSPO) and Indonesian Sustainable Palm Oil (ISPO).

“Musim Mas has long saw that smallholders are key to achieving palm oil sustainability, and that’s why we lead Indonesia’s most extensive smallholder program. We believe that the way forward is to collaborate with more partners to achieve a wider impact. With our BIPOSC partners, we hope to advance the skills and knowledge of smallholders through regenerative agriculture and related techniques. Regenerative agriculture and agroforestry have the potential to help smallholders be part of a sustainable palm oil supply chain. It could help them develop alternative sources of income, especially during the replanting period where their palm oil crops are unproductive, typically for three years,” said Rob Nicholls, General Manager, Projects & Programs, Musim Mas Group.

Musim Mas, SNV and APSKS LB share the result of 3 years BIPOSC project on promoting Regenerative Agriculture at a Press Conference in Jakarta, Indonesia on 17 October 2024

In the face of climate change and threatened biodiversity, regenerative agriculture can play a role for small farms because it maintains soil health, prevents erosion and water runoff, and can potentially reduce greenhouse gas emissions and nitrogen leakage.

“As a global development partner organization, SNV aims to support Indonesia in achieving its Sustainable Development Goals (SDGs). To achieve this, we need to implement effective and impactful programs to transform agricultural and food systems, energy, and water. In the BIPOSC program, we promote a comprehensive regenerative agriculture and agroforestry model to maintain soil fertility and biodiversity, providing maximum benefits for farmers’ livelihoods and economy,” said Rizki Pandu Permana, Country Director of SNV Indonesia.

The key regenerative agriculture techniques taught include the application of bio-input, mulching to protect topsoil, planting cover crops, integrated pest management that reduces the need for chemical pesticides, and application of compost that reduces the amount of chemical fertilizers needed. To date, 1,032 independent smallholders received training and implement these techniques on their farms, representing a total land with a total area of 1,063.68 hectares. The project trained 25 village facilitators to provide hands-on assistance to smallholders, and seven demo plots established as pilot areas and learning facilities for regenerative agriculture.

“When I visited palm oil smallholders a few years ago in the area, their biggest concern was access to more fertilizers. While fertilizers play a key role in boosting yields, there was a noticeable gap in understanding how to protect the soil from long-term degradation. Smallholders needed more knowledge about maintaining soil health, preserving soil structure, and other critical factors. This is exactly what the BIPOSC project aimed to address, and we’re pleased to see that the farmers involved are now reporting not only higher yields but also healthier soils on their plots,” said Bernard Giraud, President & Co-Founder, Livelihoods.

The projectalso looks into capacity-building. In addition to home composting, the project enabled the local farmer association, APSKS LB, to develop and manage a composting unit with a capacity of 100-150 tons/month. Producing compost at scale with inputs from nearby mills and farmer plots, the unit offers compost to member farmers at half of typical market prices. In 2023, its first year of operation, the unit produced 588 tons of compost, and generated a profit of IDR 421 million. The project partners believe it is a model that can be replicated elsewhere.

The Composting Unit Established Under the BIPOSC Project

“One of the most impactful outcomes of this project for smallholders is the Composting Unit as the business model around it. It enables smallholders to obtain compost affordably, and the profits are shared among member farmers. This is a practical solution to promote the adoption of composting, and all ASPKS-LB smallholders are now using compost in their plots,” said Syahrianto, Chairman of the Labuanbatu Independent Oil Palm Smallholders Association.

As of 2023, independent smallholders manage about 41% of oil palm planted areas in Indonesia, representing 6.94 million hectares. This figure is expected to increase to 60% by 2030, making projects like BIPOSC critical in shaping the future of sustainable palm oil production.

Devane Sharma
[email protected]

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Fintech PR

BRI Partners with Nium to Expand Real-Time Cross-Border Payment Solutions

Published

1 hour ago

October 18, 2024

CISION (PR Newswire)

bri-partners-with-nium-to-expand-real-time-cross-border-payment-solutions

JAKARTA, Indonesia, Oct. 18, 2024 /PRNewswire/ — Nium, the leading global infrastructure for real-time cross-border payments, is thrilled to announce a partnership with Bank Rakyat Indonesia (BRI) to provide Indonesian customers with real-time international money transfer capabilities. This collaboration aims to enhance the cross-border offerings for BRI’s individual and corporate customers, delivering more accessible and cost-effective financial services across Indonesia.

This partnership empowers more than 150 million BRI account holders, including those in remote regions of Indonesia, to access modern, real-time cross-border payment services. The offering includes a variety of real-time payment mechanisms, supporting bank account destinations, a global electronic card network, and digital wallets. These innovations are closely aligned with BRI’s ongoing mission to provide affordable and customer-focused financial products, particularly for traditionally underserved communities.

BRI’s Corporate Secretary, Agustya Hendy Bernadi, emphasized BRI’s dedication to constantly improving customer convenience through innovations in its global network and cross-border transaction services. “This collaboration reflects BRI’s continuous efforts to enhance productivity and efficiency by expanding its digital payment channel network to meet the growing demand for global transactions,” he said. Agustya added that the partnership with Nium aligns perfectly with BRI’s vision to be Southeast Asia’s most valuable banking group and a champion of financial inclusion by 2025. “With Nium’s global transaction network, BRI strengthens the digitalization of its business processes and enhances retail banking capabilities in line with our 2025 strategic vision.”

Anupam Pahuja, General Manager and Executive Vice President for Asia Pacific, Middle East, and Africa at Nium, shared his excitement about the partnership, highlighting BRI’s extensive presence across Indonesia’s 17,000 islands. “By integrating Nium’s advanced technology into BRI’s platform, we are dedicated to providing BRI’s customers, no matter where they are, with access to exceptional financial services. This partnership will remove the risks associated with cash handling and provide faster, more cost-effective transactions—whether individuals are sending money to family members abroad or businesses are making international payments.”

Cross-border payments are projected to grow significantly in Indonesia, with a forecasted year-on-year increase of 15% through 2025, driven largely by the digital transformation in financial services (Statista, 2024).

This partnership between BRI and Nium is expected to transform the way Indonesians engage with global financial services, meeting the rising demand for modern payment infrastructure and enhancing the overall experience for BRI’s customers in their international transactions.

About Nium

Nium, the leading global infrastructure for real-time cross-border payments, was founded on the mission to deliver the global payments infrastructure of tomorrow, today. With the onset of the global economy, its payments infrastructure is shaping how banks, fintechs, and businesses everywhere collect, convert, and disburse funds instantly across borders. Its payout network supports 100 currencies and spans 220+ markets, 100 of which in real-time. Funds can be disbursed to accounts, wallets, and cards and collected locally in 40 markets. Nium’s growing card issuance business is already available in 34 countries. Nium holds regulatory licenses and authorizations in more than 40 countries, enabling seamless onboarding, rapid integration, and compliance – independent of geography. The company is co-headquartered in San Francisco and Singapore.

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Fintech PR

Grexie Signchain Launches on November 1st, 2024: Enabling Smart Contract Developers to Bring Off-Chain Data On-Chain with Seamless Gas-Paid Signing

Published

8 hours ago

October 17, 2024

CISION (PR Newswire)

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Grexie Signchain enables developers to sign off-chain data into smart contracts, with self-hosted or secure vault signer wallet management.

MANCHESTER, England, Oct. 17, 2024 /PRNewswire/ — Grexie Limited proudly announces the launch of its innovative smart contract solution, Signchain, on November 1st, 2024. Designed specifically for developers, Signchain introduces a powerful way to bring off-chain data on-chain through user-paid gas fees and secure signing of data into smart contract methods using its extendable smart contract, Signable.

In the growing landscape of blockchain technology, securely managing off-chain data and integrating it into on-chain smart contracts has posed significant challenges for developers. Signchain eliminates these hurdles by offering a robust, gas-efficient system for signing and authenticating data in real-time.

Key Features of Signchain:

1. Seamless Off-Chain to On-Chain Data Integration
Signchain enables developers to securely bring off-chain data on-chain by signing it directly into smart contract methods through user-paid gas fees. This integration ensures that data authenticity is preserved, and its entry into the blockchain remains tamper-proof, streamlining processes for industries relying on real-world data verification. Signchain also supports integration with Google Sheets, AWS, and Firebase, making it easy to pull data from popular off-chain data sources.

2. Extendable Smart Contract – Signable
The core of Signchain’s technology is its extendable smart contract, Signable, which allows developers to customize and build upon existing smart contracts. With Signable, developers can easily implement contract signatures for any data type, offering flexibility across industries from finance to logistics and beyond.

3. Signer Wallet Management
Signchain offers comprehensive signer wallet management as part of its service, empowering developers to manage and authenticate signers effectively. Wallets can either be self-hosted using Signchain’s Docker container for those who prefer their own infrastructure, or they can leverage Signchain’s network of secure vaults for maximum security.

4. Self-Hosted or Managed Service
For developers who want full control of their infrastructure, Signchain provides a self-hosted option via Docker containers, allowing them to deploy the platform on their own servers. Alternatively, developers can opt to use Signchain’s secure vault network, offering a hassle-free solution with enterprise-grade security and wallet management.

5. User-Paid Gas Fees
By integrating a user-paid gas fee model, Signchain allows users to cover the costs of signing and authenticating their data, ensuring the signing process is efficient and doesn’t overburden developers with additional expenses. This makes Signchain an ideal solution for dApps and platforms handling high transaction volumes.

6. Google Sheets, AWS, Firebase Integration with Serverless Model
Signchain supports integration with Google Sheets, AWS, and Firebase in a serverless model, powered by a hosted Sign In With Ethereum (SIWE) implementation provided by Signchain’s API. Developers can simply connect their Google Sheets and configure the contract parameters associated with each column. Signchain will automatically look up the user’s wallet address in the spreadsheet, sign the transaction data, and execute it in the blockchain along with any user-supplied parameters. This creates an easy, efficient way to manage data inputs from off-chain sources without heavy infrastructure setup.

Revolutionizing Smart Contract Workflows

With Signchain, developers now have the tools to handle the complexities of integrating off-chain data into smart contracts. The extendable nature of Signable offers flexibility, allowing developers to cater to various use cases, whether it’s automating financial transactions, supply chain data, or verifying legal agreements.

Tim Behrsin, CEO of Grexie Limited, said, “Signchain is more than just a signing solution—it’s a platform that empowers developers to securely integrate off-chain data into their smart contracts with minimal effort. The flexibility of Signable and our focus on signer wallet management offers developers control and security at every stage of the process.”

Why Signchain Matters

Signchain addresses critical challenges faced by developers, particularly those dealing with off-chain data. By signing data into smart contracts and enabling user-paid gas fees, the platform significantly reduces friction in managing secure, scalable smart contracts. Whether developers need to manage high volumes of data transactions or create bespoke smart contracts, Signchain offers a scalable and secure solution.

In industries like DeFi, real estate, and supply chain management, data integrity and security are paramount. Signchain’s secure vault network and customizable signing workflows allow businesses to handle sensitive information with confidence.

Launch Event and Future Developments

The official launch of Signchain will take place on November 1st, 2024, alongside a virtual event. The event will showcase live demonstrations of Signable, with detailed walkthroughs of the Docker-based self-hosted solution and signer wallet management features. Attendees will also get an exclusive preview of future enhancements, including multi-signature workflows and advanced blockchain network integrations.

About Signchain

Signchain is a cutting-edge platform developed by Grexie Limited, based in Manchester, Cheshire, United Kingdom. Signchain simplifies smart contract development by offering a secure, scalable, and customizable solution for signing and authenticating off-chain data on-chain. Developers can either self-host the solution using Signchain’s Docker container or rely on the network’s secure vault infrastructure. With an emphasis on security, flexibility, and developer experience, Signchain is set to transform how smart contracts handle off-chain data.

For more information, visit signchain.net.