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EQT Life Sciences leads EUR 93 million oversubscribed Series A round in PanTera, which aims to accelerate global actinium – 225 production

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  • On track for commercial-scale production of actinium-225, which is crucial to a new class of targeted treatments for cancer
  • Largest Series A in life sciences sector in Belgium to date; led by EQT Life Sciences
  • Total of EUR 134 million raised including funding secured through EUR 7.2 million equity from IBA and SFPIM, and EUR 33.8 million debt financing

STOCKHOLM, Sept. 11, 2024 /PRNewswire/ — EQT Life Sciences is pleased to announce that it has led a EUR 93 million oversubscribed Series A fundraise in PanTera, the Belgian radioisotope producer. With additional equity and debt funding, the total amount raised is EUR 134 million. The round was also joined by Kurma Partners, Eurazeo, Korys, Paladin and PMV. Alongside this, IBA, the world leader in particle accelerator technology, and SFPIM, a Belgian sovereign fund, will convert into equity EUR 7.2 million convertible loans.

PanTera was founded in 2022 with the primary goal of enabling large-scale production of actinium-225 (225Ac), which is crucial to enable a new class of targeted cancer treatments known as Targeted Alpha Therapy. The funds raised will be used primarily to support the construction of a state-of-the-art production facility in Belgium.

Targeted Alpha Therapy is a promising new cancer treatment approach that enables safe and effective delivery of radiation to the cancer cells by radioisotopes that emit highly energetic alpha particles. The radiation effect of the alpha particle is more localized compared to other approaches and as such can destroy the cancer cells to which it is attached without harming surrounding healthy tissue. The most promising alpha emitter for this approach is 225Ac. As a result, demand for 225Ac is increasing rapidly as drug-development companies look to scale-up clinical trials across a range of different cancers and seek regulatory approvals. However, dependable, scalable and sustainable methods for producing 225Ac are complex and require advanced nuclear infrastructure, which has resulted in a global shortage of the isotope.

PanTera is working to solve this global shortage. The Company’s unique, patented photo-nuclear “gamma” production process transforms Radium-226 (226Ra) into Radium-225 (225Ra), which in turn decays into 225Ac. This process provides a reliable, safe and high-quality supply of 225Ac, not only for clinical trials but also for future commercial radiopharmaceutical therapies, the first of which are due to be on the market in 2028-2029. PanTera’s process and infrastructure is designed to enable the annual production of more than 100 Curies (Ci) of clinical grade 225Ac by 2029, allowing treatment of more than 100,000 patients per year. The combination of SCK CEN’s unmatched large stock of pure 226Ra and IBA’s Rhodotron® electron accelerator, positions PanTera to become a highly successful and reliable producer of this key medical radioisotope.

In parallel to its effort to develop commercial-scale production of 225Ac, PanTera is already providing early 225Ac supply through an alternative production method. Working in collaboration with TerraPower Isotopes, PanTera is on track to provide 1.5-2 Ci of 225Ac annually from early 2025. With today’s current global supply estimated at 3 Ci annually, this will be a significant contribution to drug development. PanTera has signed supply agreements with several pharmaceutical companies, including Bayer, and expects to have secured agreements for more than 80% of its capacity before starting production.

Sven Van den Berghe, CEO of PanTera, said: “PanTera is looking to radically improve supply in the short and long term, in order to ensure that this potentially life-saving, highly innovative modality can reach patients. The size of this raise is testament to our strategy, our unique assets and our capabilities. We are working alongside very experienced partners with a combined expertise and a network that goes well beyond 225Ac production and encompasses all aspects of the radiopharmaceutical revolution. With this funding, we are now en route to realise our vision of providing a “Better Fight for Life” to cancer patients worldwide by becoming a dependable global 225Ac supplier.”

Martijn Kleijwegt, Partner at EQT Life Sciences, commented: “It is clear to us that PanTera has the expertise, assets and strategy in place to address the critical actinium-225 supply shortage faced by the pharmaceutical industry today, as well as the significant increase in demand expected in the future. EQT is one of the world’s largest healthcare investors and we are committed to supporting pioneering ventures, like PanTera, to reach their fullest potential. We are excited to partner with the PanTera team, alongside IBA, SCK CEN and our fellow investors, on the next phase of PanTera’s development.”

Contact
EQT Press Office, [email protected] 

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Matrixdock Partners with Brink’s for Global RWA Custody, Starting with Gold

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Partnership Enhances Security for XAUm, Matrixdock’s Gold-Backed Digital Asset, with a Focus on Key Asian Financial Hubs

SINGAPORE, Nov. 25, 2024 /PRNewswire/ — Matrixdock, a leading platform for tokenized real-world assets (RWA), is pleased to announce a strategic partnership with Brink’s, a global leader in secure logistics and asset protection. This partnership ensures the secure transportation and vaulting of LBMA-certified gold, which underpins Matrixdock’s recently launched XAUm token, with a focus on vaults located in Singapore and Hong Kong, two of Asia’s premier financial hubs.

XAUm, an ERC-20 token fully backed by physical gold, offers investors a trusted and transparent digital asset tied to London Bullion Market Association (LBMA) accredited gold. The partnership with Brink’s guarantees that the gold reserves backing XAUm are securely held in high-security, fully insured vaults in Singapore and Hong Kong, enhancing the credibility and security of the token for investors across the globe, particularly in the Asia-Pacific region.

“Brink’s reputation for excellence in secure logistics, combined with the strategic location of vaults in Singapore and Hong Kong, provides unparalleled security and confidence for our XAUm investors,” said Eva Meng, Head of Matrixdock. “This partnership underscores our commitment to maintaining the highest standards of trust and transparency for our tokenized real-world assets.”

Zac McKenna, Head of Digital Assets at Brink’s, emphasized the importance of secure custody solutions in the growing RWA tokenization space: “At Brink’s, we are proud to support the tokenization of real-world assets by providing the secure infrastructure that makes these digital products credible and reliable. Our collaboration with Matrixdock enables us to bring our extensive expertise in secure logistics to the forefront of the blockchain ecosystem.”

Brink’s, with its extensive experience in secure asset management and its well-established presence in Asia, will ensure that the LBMA gold backing XAUm is safely transported, stored, and protected in its world-class vaults. Ben Van Kerkwijk, Vice President of Brink’s Global Services – Asia Pacific, added: “Our premier vaulting facilities in Singapore and Hong Kong are trusted by top-tier clients around the world. We are pleased to provide the same world-class protection for the physical gold that backs Matrixdock’s XAUm token, further enhancing the security and trust for investors in the region.”

This partnership allows Matrixdock to offer a robust gold-backed digital asset that aligns with the security and regulatory requirements of global investors.

XAUm provides investors with seamless access to the value of physical gold while benefiting from the efficiency, liquidity, and transparency of blockchain technology. By focusing on secure vaulting in Singapore and Hong Kong, Matrixdock strengthens its offering in the growing Asian market for tokenized assets.

For more information, please visit www.matrixdock.com.

About Matrixdock

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Founded in February 2023 by Matrixport, Matrixdock is a premier platform that offers access to high-quality Real World Assets (RWA) through advanced tokenization technology. As the first in Asia to introduce a tokenized short-term treasury bill product, STBT, Matrixdock has rapidly emerged as an industry leader, earning the Ecosystem Excellence TADS Award in 2023 for Trading & Liquidity Solutions.

Matrixdock is dedicated to becoming the gateway for clients seeking top-tier RWA investments. With a steadfast focus on building a trusted and secure RWA ecosystem for crypto, Matrixdock provides diversified investment opportunities while setting new standards for trust and governance in the digital asset space.

About Brink’s

The Brink’s Company (NYSE:BCO) is a leading global provider of cash and valuables management, digital retail solutions, and ATM managed services. Our customers include financial institutions, retailers, government agencies, mints, jewelers, and other commercial operations. Our network of operations in 52 countries serves customers in more than 100 countries.

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Cboe Clear Europe Secures Regulatory Approval to Launch Securities Financing Transactions Clearing

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AMSTERDAM and LONDON, Nov. 25, 2024 /PRNewswire/ — Cboe Clear Europe, a leading pan-European clearing house, today announced that it has received regulatory approval to clear European Securities Financing Transactions (SFTs). This was granted by De Nederlandsche Bank (DNB) and the Autoriteit Financiële Markten (AFM).

With this approval, Cboe Clear Europe is set to introduce a first-of-its-kind service for European SFT transactions in cash equities and ETFs, which includes central clearing, settlement and post-trade lifecycle management. It is available to principal lenders, special participant lenders (UCITS and non-UCITS) and borrowers, with settlements conducted across 19 European Central Securities Depositories (CSDs).

The service supports key regulatory initiatives such as the European Market Infrastructure Regulation (EMIR), Central Securities Depositary Regime (CSDR) and the Securities Financing Transactions Regulation (SFTR), thereby promoting transparency, market integrity and the competitiveness of European capital markets.

“We are delighted to have received regulatory approval to expand into European SFT clearing, marking a significant milestone in our goal to introduce innovative, robust, and comprehensive clearing solutions across multiple asset classes in Europe,” said Vikesh Patel, President of Cboe Clear Europe. “This achievement underscores our dedication to supporting our clients’ evolving needs and contributing to the resilience of financial markets. We greatly appreciate the support of our regulators as we deliver on our commitment to launch innovative services which we believe enhance efficiencies for European market participants and help foster the growth of the region’s capital markets.”

This service will help to transform the current bilateral process between securities lenders and borrowers into a centrally cleared model, with Cboe Clear Europe acting as the counterparty to both sides of each transaction. We believe this enables participants to reduce their risk-weighted asset exposures associated with SFTs and supports the growth of this key market. Additionally, it is expected to bring various capital and operational advantages, including savings from cross-margining between cash equities and SFTs, greater settlement efficiencies, elimination of agent lender disclosures, and improved practices around fees management and corporate actions.

The service will utilise The Bank of New York Mellon Corporation and J.P. Morgan as Tri-Party Collateral Agents, while Pirum will serve as the transmitter of new trade instructions and post-trade lifecycle events on behalf of clients.

Jan Treuren, Senior Director, Product, Cboe Clear Europe, said: “We are excited to build out this new clearing eco-system in collaboration with market participants and are already in advanced discussions with a wide variety of firms, including banks, asset managers, broker-dealers, and Agent Lenders – representing beneficial owners like pension funds and UCITS – to help ensure a smooth launch in the coming weeks and months. This service is supported by our best-in-class risk management framework, offering clients the advantage of Cboe Clear Europe’s extensive settlement experience and broad direct connectivity to 19 European CSDs. Initially, the service will cover key European markets, with plans to expand the offering based on client demand and market developments.”

As a leading pan-European cash equities clearing house, Cboe Clear Europe currently provides its services for 47 trading venues, achieving a record cash equity market share of 37.2%* in Q3 2024. The company enables Clearing Participants to manage their counterparty credit risk and also to maximise operational efficiencies through automated processing and the provision of netting opportunities. It diversified into equity derivatives clearing in 2021 to support the launch of Cboe Europe Derivatives (CEDX), Cboe’s pan-European equity derivatives exchange, which includes equity index and single stock derivatives.

Further information on the company and its services can be found here: clear.cboe.com/europe

*Source: Cboe Clear Europe estimates

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About Cboe Global Markets, Inc.

Cboe Global Markets (Cboe: CBOE), the world’s leading derivatives and securities exchange network, delivers cutting-edge trading, clearing and investment solutions to people around the world. Cboe provides trading solutions and products in multiple asset classes, including equities, derivatives and FX, across North America, Europe and Asia Pacific. Above all, we are committed to building a trusted, inclusive global marketplace that enables people to pursue a sustainable financial future. To learn more about the Exchange for the World Stage, visit www.cboe.com.

Media Contacts

Cboe Analyst Contact

Angela Tu 

Tim Cave

Kenneth Hill, CFA 

+1-646-856-8734 

 +44 (0) 7593-506-719

+1-312-786-7559 

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Cboe®, Cboe Clear®, and Cboe Global Markets® are registered trademarks of Cboe Exchange, Inc. All other trademarks and service marks are the property of their respective owners.

Cboe Global Markets, Inc.  and its affiliates do not recommend or make any representation as to possible benefits from any securities, futures, digital assets or investments, or third-party products or services. Cboe Global Markets, Inc. is not affiliated with BNY, JP Morgan, and Pirum. Investors should undertake their own due diligence regarding their securities, futures, digital assets, and investment practices. This press release speaks only as of this date. Cboe Global Markets, Inc. disclaims any duty to update the information herein.

Nothing in this announcement should be considered a solicitation to buy or an offer to sell any securities, futures, or digital assets in any jurisdiction where the offer or solicitation would be unlawful under the laws of such jurisdiction. Nothing contained in this communication constitutes tax, legal or investment advice.  Investors must consult their tax adviser or legal counsel for advice and information concerning their particular situation.

Cboe Global Markets, Inc.  and  its  affiliates make  no  warranty,  expressed  or  implied,  including,  without  limitation,  any  warranties  as  of  merchantability,  fitness  for  a particular  purpose,  accuracy,  completeness  or  timeliness,  the  results to  be  obtained  by  recipients  of  the  products  and  services  described  herein.

Cautionary Statements Regarding Forward-Looking Information

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that involve a number of risks and uncertainties. You can identify these statements by forward-looking words such as “may,” “might,” “should,” “expect,” “plan,” “anticipate,” “believe,” “estimate,” “predict,” “potential” or “continue,” and the negative of these terms and other comparable terminology. All statements that reflect our expectations, assumptions or projections about the future other than statements of historical fact are forward-looking statements. These forward-looking statements, which are subject to known and unknown risks, uncertainties and assumptions about us, may include projections of our future financial performance based on our growth strategies and anticipated trends in our business. These statements are only predictions based on our current expectations and projections about future events. There are important factors that could cause our actual results, level of activity, performance or achievements to differ materially from those expressed or implied by the forward-looking statements.

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We operate in a very competitive and rapidly changing environment. New risks and uncertainties emerge from time to time, and it is not possible to predict all risks and uncertainties, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements.

Some factors that could cause actual results to differ include: the loss of our right to exclusively list and trade certain index options and futures products; economic, political and market conditions; compliance with legal and regulatory obligations; price competition and consolidation in our industry; decreases in trading or clearing volumes, market data fees or a shift in the mix of products traded on our exchanges; legislative or regulatory changes or changes in tax regimes; our ability to protect our systems and communication networks from security vulnerabilities and breaches; our ability to attract and retain skilled management and other personnel; increasing competition by foreign and domestic entities; our dependence on and exposure to risk from third parties; global expansion of operations; factors that impact the quality and integrity of our and other applicable indices; our ability to manage our growth and strategic acquisitions or alliances effectively;  our ability to operate our business without violating the intellectual property rights of others and the costs associated with protecting our intellectual property rights; our ability to minimize the risks, including our credit, counterparty, investment, and default risks, associated with operating a European clearinghouse; our ability to accommodate trading and clearing volume and transaction traffic, including significant increases, without failure or degradation of performance of our systems; misconduct by those who use our markets or our products or for whom we clear transactions; challenges to our use of open source software code; our ability to meet our compliance obligations, including managing potential conflicts between our regulatory responsibilities and our for-profit status; our ability to maintain BIDS Trading as an independently managed and operated trading venue, separate from and not integrated with our registered national securities exchanges; damage to our reputation; the ability of our compliance and risk management methods to effectively monitor and manage our risks; restrictions imposed by our debt obligations and our ability to make payments on or refinance our debt obligations; our ability to maintain an investment grade credit rating; impairment of our goodwill, long-lived assets, investments or intangible assets; the impacts of pandemics; the accuracy of our estimates and expectations; litigation risks and other liabilities; and risks relating to digital assets, including winding down the Cboe Digital spot market and transitioning digital asset futures contracts to CFE, operating a digital assets futures clearinghouse, cybercrime, changes in digital asset regulation, and fluctuations in digital asset prices. More detailed information about factors that may affect our actual results to differ may be found in our filings with the SEC, including in our Annual Report on Form 10-K for the year ended December 31, 2023 and other filings made from time to time with the SEC.

We do not undertake, and we expressly disclaim, any duty to update any forward-looking statement whether as a result of new information, future events or otherwise, except as required by law. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof.

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Ultima Markets Spotlights the Future of CRM Technology at FMLS:24

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LONDON, Nov. 25, 2024 /PRNewswire/ — Ultima Markets established itself as a forward-thinking leader within the financial industry at the esteemed Finance Magnates London Summit 2024 (FMLS:24). The summit attracted a diverse group of industry professionals, all eager to explore the transformative trends shaping financial services’ future.

Our booth set a high bar for energy and engagement among the distinguished participants. We transformed the typical expo experience into an immersive showcase for financial enthusiasts. With a vibrant display and interactive offerings, it became the summit’s focal point, attracting a diverse crowd eager to dive into the trading world.

The summit featured various sessions, including interviews, panel discussions, and keynote speeches. Topics ranged from regulatory frameworks to the digital revolution in finance, aimed at sparking conversation and shaping the industry’s future.

Redefining CRM with Artificial Intelligence

Ultima Markets took a prominent role during the summit, with our Vice President of Marketing, Ernest Yiu, delivering a highly anticipated keynote speech on ‘CRM in 2025: The Light at the End of the Funnel’.

Ernest Yiu, Vice President of Marketing, Ultima Markets, speaking at FMLS:24

“The future of CRM was evolving rapidly,” he said, “thanks to AI and machine learning. These tools enabled brokers to predict client needs by analysing behaviours and preferences, allowing us to provide more personalised and proactive service.”

He also stressed the importance of personalisation in client relationships: “At Ultima Markets, we aimed to make clients feel like we were speaking to them directly. We achieved this by segmenting our clients based on factors like trading history and experience level, providing tailored content for each group.”

Ernest’s predictions on the practical applications of AI and machine learning encouraged the audience to reconsider their strategies, highlighting the essential role of innovative CRM solutions in maintaining a competitive edge.

FMLS:24 provided a platform for forward-thinking professionals to address the complexities of the modern financial landscape, where participants like Ultima Markets demonstrated how technology shapes the industry’s future and how companies adapt to these changes.

Ultima Markets remains committed to driving innovation and empowering traders worldwide with cutting-edge tools and insights as the financial industry evolves.

About Ultima Markets

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Ultima Markets is a fully licensed, fast-growing broker offering access to over 250+ financial instruments. With a team of more than 2,000 professionals across 15 global offices, we serve clients in 172 countries. For more information about Ultima Markets, please visit us on Facebook, X, Instagram, LinkedIn and YouTube.

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