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Soligenix Develops Groundbreaking Vaccine Platform to Target Future Pandemics

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Soligenix discusses its contribution to addressing future serious public health threats in a podcast

New York, New York–(Newsfile Corp. – September 14, 2021) – PCG Digital — The COVID-19 pandemic has already cost the United States an estimated $16 trillion in lost economic output, and has resulted in the loss of over 600,000 lives. At the end of last month, the country reached the dubious milestone of 39 million diagnosed cases of COVID, however, researchers have estimated a further 4.8 undiagnosed cases per diagnosis, bringing the nation’s total number of infections closer to 200 million.

The burden the pandemic has placed on US economic and healthcare infrastructure, and the threat of the next pandemic, has forced leaders across the country to pay close attention to pandemic preparedness.

To hear the audio version please follow the link here
To view the video version please follow the link here

Last week, the Biden administration laid out a $65 billion plan for combating biological threats, including $24.2 billion to develop new vaccines for a range of viruses and enhance distribution and manufacturing of vaccines. This is the administration’s largest proposed investment in its plan to combat pandemics.

Scientists were able to respond to COVID-19, developing a number of vaccines with unprecedented speed, because years had been spent on studying coronaviruses, allowing the scientific community to act once the virus’ genetic sequence was available. In July, Dr. Anthony Fauci encouraged the US government to take steps to prepare for future pandemics by developing vaccine prototypes for 20 virus families. Among these viruses are filoviruses, including Ebolavirus and Marburgvirus, which have the potential to be serious public health threats.

Filoviruses have been described as a “real pandemic threat.” They are highly lethal, with mortality rates in outbreaks reaching 90%, and outbreaks are increasing in frequency. The urgency of developing prototype vaccines for filoviruses can’t be understated. In response, late-stage biopharmaceutical company, Soligenix (NASDAQ: SNGX), has been focused on developing safe and effective filovirus vaccine candidates, and announced positive preclinical data with multiple heat stable candidates, demonstrating potency and efficacy, in August.

With filovirus outbreaks most commonly occurring in regions with limited access to cold chain storage, or with uncertain power supply for keeping vaccines cold to maintain their integrity, Soligenix believes its thermostable vaccine platform may be an important contributor to addressing future health emergencies.

Dr. Fauci’s recommendation highlighted the need to treat potential outbreaks at their source, typically in locations that struggle to meet the stringent cold chain requirements for many vaccines. A thermostabilized vaccine in a single-vial format would significantly enhance any public health response to a new outbreak.

Soligenix has demonstrated the feasibility of rapid and efficient manufacturing, as well as the ability to thermostabilize multiple antigens that can then be stored at temperatures exceeding 100 degrees Fahrenheit. The company intends to use its ThermoVax® vaccine platform to accelerate its joint COVID-19 vaccine effort, CiVax™. Soligenix, having received over $60 million in non-dilutive government grant and contract awards to date across their development pipeline, may be well positioned to potentially secure additional government funding under Biden’s $65 billion plan for combating biological threats. Soligenix also reported a strong cash position of approximately $29 million on June 30, 2021, separate from their current non-dilutive government funding.

Like the government, investors have also taken a new interest in infectious diseases and biological threats to human health. After a year of outperforming the market in 2020, biotech is still in favor, with two funds launched during the pandemic vastly outperforming broader biotech ETFs. Top holdings in the funds’ portfolios include key players in global efforts to deliver a vaccine for COVID-19, and the ongoing pandemic and industry focus on vaccine developments may continue to be beneficial for biotech ETFs. This is a space to watch in 2021 and beyond … as is Soligenix.

Disclaimer
This communication was produced by PCG Digital Holdings, LLC, an affiliate of PCG Advisory Inc., (together “PCG”). PCG is not a registered or licensed broker-dealer nor investment adviser. No information contained in this communication constitutes an offer to sell, a solicitation of an offer to buy, or a recommendation of any security. PCG may be compensated by respective clients for publicizing information relating to its client’s securities. See www.pcgadvisory.com/disclosures.

PCG Digital
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646-863-6341

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/96370

Fintech

Central banks and the FinTech sector unite to change global payments space

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The BIS, along with seven leading central banks and a cohort of private financial firms, has embarked on an ambitious venture known as Project Agorá.

Named after the Greek word for “marketplace,” this initiative stands at the forefront of exploring the potential of tokenisation to significantly enhance the operational efficiency of the monetary system worldwide.

Central to this pioneering project are the Bank of France (on behalf of the Eurosystem), the Bank of Japan, the Bank of Korea, the Bank of Mexico, the Swiss National Bank, the Bank of England, and the Federal Reserve Bank of New York. These institutions have joined forces under the banner of Project Agorá, in partnership with an extensive assembly of private financial entities convened by the Institute of International Finance (IIF).

At the heart of Project Agorá is the pursuit of integrating tokenised commercial bank deposits with tokenised wholesale central bank money within a unified, public-private programmable financial platform. By harnessing the advanced capabilities of smart contracts and programmability, the project aspires to unlock new transactional possibilities that were previously infeasible or impractical, thereby fostering novel opportunities that could benefit businesses and consumers alike.

The collaborative effort seeks to address and surmount a variety of structural inefficiencies that currently plague cross-border payments. These challenges include disparate legal, regulatory, and technical standards; varying operating hours and time zones; and the heightened complexity associated with conducting financial integrity checks (such as anti-money laundering and customer verification procedures), which are often redundantly executed across multiple stages of a single transaction due to the involvement of several intermediaries.

As a beacon of experimental and exploratory projects, the BIS Innovation Hub is committed to delivering public goods to the global central banking community through initiatives like Project Agorá. In line with this mission, the BIS will soon issue a call for expressions of interest from private financial institutions eager to contribute to this ground-breaking project. The IIF will facilitate the involvement of private sector participants, extending an invitation to regulated financial institutions representing each of the seven aforementioned currencies to partake in this transformative endeavour.

Source: fintech.globa

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TD Bank inks multi-year strategic partnership with Google Cloud

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TD Bank has inked a multi-year deal with Google Cloud as it looks to streamline the development and deployment of new products and services.

The deal will see the Canadian banking group integrate the vendor’s cloud services into a wider portion of its technology solutions portfolio, a move which TD expects will enable it “to respond quickly to changing customer expectations by rolling out new features, updates, or entirely new financial products at an accelerated pace”.

This marks an expansion of the already established relationship between TD Bank and Google Cloud after the group previously adopted the vendor’s Google Kubernetes Engine (GKE) for TD Securities Automated Trading (TDSAT), the Chicago-based subsidiary of its investment banking unit, TD Securities.

TDSAT uses GKE for process automation and quantitative modelling across fixed income markets, resulting in the development of a “data-driven research platform” capable of processing large research workloads in trading.

Dan Bosman, SVP and CIO of TD Securities, claims the infrastructure has so far supported TDSAT with “compute-intensive quantitative analysis” while expanding the subsidiary’s “trading volumes and portfolio size”.

TD’s new partnership with Google Cloud will see the group attempt to replicate the same level of success across its entire portfolio.

Source: fintechfutures.com

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MAS launches transformative platform to combat money laundering

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The MAS has unveiled Cosmic, an acronym for Collaborative Sharing of Money Laundering/Terrorism Financing Information and Cases, a new money laundering platform.

According to Business Times, launched on April 1, Cosmic stands out as the first centralised digital platform dedicated to combating money laundering, terrorism financing, and proliferation financing on a worldwide scale. This move follows the enactment of the Financial Services and Markets (Amendment) Act 2023, which, along with its subsidiary legislation, commenced on the same day to provide a solid legal foundation and safeguards for information sharing among financial institutions (FIs).

Cosmic enables participating FIs to exchange customer information when certain “red flags” indicate potential suspicious activities. The platform’s introduction is a testament to MAS’s commitment to ensuring the integrity of the financial sector, mandating participants to establish stringent policies and operational safeguards to maintain the confidentiality of the shared information. This strategic approach allows for the efficient exchange of intelligence on potential criminal activities while protecting legitimate customers.

Significantly, Cosmic was co-developed by MAS and six leading commercial banks in Singapore—OCBC, UOB, DBS, Citibank, HSBC, and Standard Chartered—which will serve as participant FIs during its initial phase. The initiative emphasizes voluntary information sharing focused on addressing key financial crime risks within the commercial banking sector, such as the misuse of legal persons, trade finance, and proliferation financing.

Loo Siew Yee, assistant managing director for policy, payments, and financial crime at MAS, highlighted that Cosmic enhances the existing collaboration between the industry and law enforcement authorities, fortifying Singapore’s reputation as a well-regulated and trusted financial hub. Similarly, Pua Xiao Wei of Citi Singapore and Loretta Yuen of OCBC have expressed their institutions’ support for Cosmic, noting its potential to ramp up anti-money laundering efforts and its significance as a development in the banking sector’s ability to combat financial crimes efficiently. DBS’ Lam Chee Kin also praised Cosmic as a “game changer,” emphasizing the careful balance between combating financial crime and ensuring legitimate customers’ access to financial services.

Source: fintech.global

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