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Highlights and Insights into Soligenix

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Dr. Chris Schaber Discusses Soligenix HyBryte(TM) and Thermostabilized Vaccines

New York, New York–(Newsfile Corp. – October 13, 2021) – PCG Digital — In a recent interview with Kristen Kluska, a biotechnology analyst at Cantor, Dr. Chris Schaber, President and CEO of Soligenix (NASDAQ: SNGX), spoke about the latest developments with their synthetic hypericin topical treatment HyBryte™ and the Company’s ongoing research and development of thermostabilized vaccine candidates for filoviruses and COVID-19.

The interview took place at the Cantor Fitzgerald Global Health Care Conference, which was held virtually from September 27-30, 2021. Biotechnology and pharmaceuticals were key areas of discussion. Over three hundred companies in the healthcare sector were represented.

HyBryte™ as a Safer Treatment for Cutaneous T-Cell Lymphoma (CTCL)

The first topic of the virtual fireside chat was Soligenix orphan drug candidate HyBryte™, a treatment option for cutaneous T-cell lymphoma (CTCL). There is currently no uniformly accepted treatment for the condition, which is a chronic cancer. The use of the synthetic hypericin in HyBryte™ with safe, visible fluorescent light is an option for early-stage patients.

“With traditional phototherapy treatments, the activation of the singlet oxygen in hypericin induces necrosis and apoptosis in adjacent cells,” Dr. Schaber shared. “For early-stage patients, it is a balancing act between treating the lesions and minimizing the long-term toxicities of the treatments. The ability to activate HyBryte™ with visible light makes it a safer alternative.”

In 2020, the results of a Phase 3 FLASH trial of HyBryte™ revealed a statistically significant treatment response. 49% of the patients showed a 50% improvement in their index lesions. It was also discovered that HyBryte™ worked well on both patch and deeper plaque lesions. An NDA filing for the drug is expected in 2022, with US commercialization planned for 2023.

Public Health Solutions with Thermostabilized Vaccines

One of the challenges with COVID-19 vaccines currently approved for use is the need to ship and store them in sub-zero temperatures. This hampers logistics, particularly in countries with poor infrastructure and power grids. Soligenix, using a technology platform already being tested with filovirus vaccines, is developing CiVax™ a thermostabilized Sars-CoV-2 vaccine candidate.

“Soligenix has been working on filovirus vaccine solutions for Ebola and Marburg, with a focus on eliminating the need for refrigerated storage and shipping,” Dr. Schaber shared. “Ebola is endemic in Africa, in areas with power grid problems and challenging distribution logistics. The need created a demand for a better solution. We’ve come up with one.”

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“The work on filovirus vaccines allowed us to demonstrate thermostabilization of a different kind of adjuvant, one more appropriate for the immunity needed against viruses, which includes both antibody (humoral) and cell mediated immunity. In early-stage testing, we’ve already shown immunogenicity in both mice and non-human primates.”

Late-Breaking News

Shortly after the conference, Soligenix announced accelerated publication demonstrating that its CiVax™ COVID-19 vaccine yields broad neutralizing antibody responses against the original strain and Beta, Gamma and Delta variants in non-human primates.

“We believe that creating a COVID-19 vaccine, like CiVax™, with enhanced stability at elevated temperatures has the potential to lead to a faster resolution of this global pandemic, curtailing the further evolution of the virus,” stated Dr. Schaber. “Moreover, the introduction of a subunit vaccine that has been built on years of proven vaccine technology may also encourage the vaccine-hesitant. This platform not only has the potential to aid in the current worldwide pandemic; but the technology platform, with its broad applicability, may also aid in the preparation for future pandemics. With these latest results, we will be expanding discussions with various funding agencies in the coming weeks.”

Leveraging Government Grants and Contracts

In their Public Health Solutions segment, which includes vaccine development, Soligenix has sought to leverage government grants and contracts, a non-dilutive way to advance significant programs. To date, they’ve managed to raise over $60 million this way. The company currently has a cash runway of $29 million, enough to fund research well into 2023.

With a strong financial outlook and several of their products advancing towards late-stage trials, Soligenix is well positioned to execute on multiple fronts across their pipeline, including HyBryte™ commercialization. To learn more about their Public Health Solutions or orphan drug candidates, visit https://www.soligenix.com/.

Disclaimer
This communication was produced by PCG Digital Holdings, LLC, an affiliate of PCG Advisory Inc., (together “PCG”). PCG is not a registered or licensed broker-dealer nor investment adviser. No information contained in this communication constitutes an offer to sell, a solicitation of an offer to buy, or a recommendation of any security. PCG may be compensated by respective clients for publicizing information relating to its client’s securities. See www.pcgadvisory.com/disclosures.

PCG Digital
[email protected]
646-863-6341

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To view the source version of this press release, please visit https://www.newsfilecorp.com/release/99351

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Fintech Pulse: Your Daily Industry Brief (Chime, ZBD, MiCA)

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As we close out 2024, the fintech industry continues to deliver headlines that underscore its dynamism and innovation. From IPO aspirations to groundbreaking regulatory milestones, today’s updates highlight the transformative power of fintech partnerships, regulatory evolution, and disruptive technologies. Here’s what you need to know.

Chime’s Quiet Step Toward Public Markets

Chime, the U.S.-based financial technology startup best known for its digital banking services, has taken a significant step by filing confidential paperwork for an initial public offering (IPO). As one of the most valuable private fintechs in the U.S., Chime’s move could potentially signal a renewed appetite for fintech IPOs in a market that has been cautious following fluctuating valuations across the tech sector.

With a valuation that reportedly exceeded $25 billion in its last funding round, Chime’s IPO could set a new benchmark for the industry. Observers note that its strong customer base and revenue growth may make it an appealing choice for investors seeking to capitalize on the digital banking boom. However, the timing and success of the IPO will depend on broader market conditions and the regulatory landscape.

Source: Bloomberg

ZBD’s Pioneering Achievement: EU MiCA License Approval

ZBD, a fintech company specializing in Bitcoin Lightning network solutions, has made history by becoming the first to secure an EU MiCA (Markets in Crypto-Assets Regulation) license. This landmark approval by the Dutch regulator positions ZBD at the forefront of compliant crypto-fintech operations in Europe.

MiCA, which aims to harmonize the regulatory framework for crypto-assets across the EU, has been a focal point for industry players aiming to establish legitimacy and expand their offerings. ZBD’s achievement not only validates its operational rigor but also sets a precedent for other fintech firms navigating the evolving regulatory landscape.

Industry insiders view this as a strategic advantage for ZBD as it broadens its footprint in Europe. By leveraging its regulatory approval, the company can accelerate its product deployment and establish trust with institutional and retail users alike.

Source: Coindesk, PR Newswire

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The Fintech-Credit Union Synergy: A Blueprint for Innovation

The convergence of fintechs and credit unions continues to reshape the financial services ecosystem. Collaborative initiatives, such as the one highlighted in the recent partnership between fintech innovators and credit unions, are proving to be a potent force in delivering tailored financial solutions.

This “dream team” approach allows credit unions to leverage fintech’s technological expertise while maintaining their community-focused ethos. Key areas of collaboration include digital payments, personalized financial management tools, and enhanced loan processing capabilities. These partnerships not only enhance member engagement but also enable credit unions to remain competitive in an increasingly digital-first financial environment.

Industry analysts emphasize that such collaborations underscore a broader trend of traditional financial institutions embracing fintech-driven solutions to bridge service gaps and foster innovation.

Source: PYMNTS

Tackling Student Loan Debt: A Fintech’s Mission

Student loan debt remains a pressing issue for millions of Americans, and a Rochester-based fintech aims to offer relief through its cloud-based platform. This innovative solution is designed to simplify loan management and provide borrowers with actionable insights to reduce their debt burden.

The platform’s features include repayment optimization tools, personalized financial education, and seamless integration with loan servicers. By addressing the complexities of student loan management, this fintech is empowering borrowers to make informed decisions and achieve financial stability.

As the student loan crisis continues to evolve, solutions like this highlight the critical role fintech can play in addressing systemic financial challenges while fostering financial literacy and inclusion.

Source: RBJ

Industry Implications and Takeaways

Today’s updates underscore several key themes shaping the fintech landscape:

  1. Regulatory Milestones: ZBD’s MiCA license approval exemplifies the importance of regulatory compliance in unlocking growth opportunities.
  2. Strategic Partnerships: The collaboration between fintechs and credit unions demonstrates the value of combining technological innovation with traditional financial models to drive customer-centric solutions.
  3. Market Opportunities: Chime’s IPO move reflects a potential revival in fintech public offerings, signaling confidence in the sector’s long-term prospects.
  4. Social Impact: Fintech’s ability to tackle systemic issues, such as student loan debt, showcases its role as a force for positive change.

 

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SPAYZ.io prepares for iFX EXPO Dubai 2025

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Leading global payments platform SPAYZ.io has confirmed it will be attending iFX EXPO Dubai 2025 on 14 to 16 January. Exhibiting at Stand 64 at Trade Centre Dubai, SPAYZ.io’s team of professionals will be on hand providing live demonstrations of its renowned payment services for payment providers. Attendees will also receive exclusive insight into SPAYZ.io’s plans for 2025 alongside early early access to its upcoming plans for the new year.

SPAYZ.io delivers a host of payment solutions that leverage the latest technological innovations and open access to the fastest growing emerging markets across Africa, Europe and Asia. Over the past year, there has been huge demand for its Open Banking and local payment method services, alongside bank transfers, mass payouts, online banking and e-wallets.

Yana Thakurta, Head of Business Development at SPAYZ.io commented: “We look forward to once again participating at iFX Dubai to expand our network of partners and clients. It’s a fantastic way to kick off the year, connecting with thousands of industry leaders from FOREX platforms to trading companies, and everything in between.

“Our key goal for iFX Dubai EXPO 2025 is to expand our portfolio of solutions and geographies. We’re using this as an opportunity to partner with like-minded entities who share our ambition to provide payment solutions that are truly global.”

Come meet SPAYZ.io’s team at the Trade Centre Dubai at Stand 64. You can also book a meeting slot with a member of a team.

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Airtm Enhances Its Board of Directors with Two Strategic Appointments

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Airtm, the most connected digital dollar account in the world, is proud to announce the addition of two distinguished industry leaders to its Board of Directors: Rafael de la Vega, Global SVP of Partnerships at Auctane, and Shivani Siroya, CEO & Founder of Tala. These appointments reflect Airtm’s commitment to innovation and financial inclusion as the company enters its next phase of growth.

“We are thrilled to welcome Rafael and Shivani to Airtm’s Board of Directors,” said Ruben Galindo Steckel, Co-founder and CEO of Airtm. “Their unique perspectives and proven track records will be invaluable as we continue scaling our platform to empower individuals and businesses in emerging markets. Together, we’ll push the boundaries of financial inclusion and innovation to create a more connected and equitable global economy. Rafael and Shivani bring a wealth of experience and strategic insight that will strengthen Airtm’s mission to connect emerging economies with the global market.”

Rafael de la Vega, a seasoned leader in fintech global partnerships and technology innovation, is currently the Global SVP of Partnerships at Auctane. With a proven track record of delivering scalable, impactful solutions at the intersection of fintech, innovation, and commerce, Rafael’s expertise will be pivotal as Airtm continues to grow. “Airtm has built a platform that breaks down barriers and opens up opportunities for people in emerging economies to connect to global markets. I am excited to contribute to its growth and help further its mission of fostering financial inclusion on a global scale,” said Rafael.

Shivani Siroya, CEO and Founder of Tala, is a pioneer in financial technology, renowned for empowering underserved communities through access to credit and essential financial tools. Her leadership in leveraging data-driven innovation aligns seamlessly with Airtm’s vision of creating more equitable financial opportunities. “Empowering underserved communities has always been at the core of my work, and Airtm’s mission resonates deeply with me. I’m thrilled to join the Board and work alongside such a dynamic team to expand access to financial tools that truly make a difference in people’s lives,” said Shivani.

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