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Fintech

Changing Lives, Delivering Value: Quoin Pharmaceuticals is Making the Balancing Act Look Easy

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New York, New York–(Newsfile Corp. – February 8, 2022) – PCG Digital – Emerging specialty pharma company, Quoin Pharmaceuticals (NASDAQ: QNRX), coined the phrase ‘Rare diseases are only rare if you don’t live with one’ to emphasize its own mission: to deliver unique solutions to help treat rare disorders that have no approved treatments or cures.

Quoin Pharmaceuticals

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Quoin has a proven ability to take a product from concept through to commercialization, thanks to the credentials of the management team who have a highly successful track record of product development, M&A, IPOs, deal making and fundraising of more than $200 million in public and private markets.

Biotechs count on an innovative pipeline and external collaborations for growth, scaling and fundraising. As a biotech focused on developing and commercializing therapeutic products for rare diseases, Quoin has shown it has all of the above: the ability to raise money and make judicious use of it to advance the company while delivering value for investors.

With its promising pipeline of clinical-stage products, clear pathway to regulatory approval and smart strategy for getting therapeutics to those who need them most, Quoin seems poised for success. We sat down with Michael Myers, CEO of Quoin Pharmaceuticals, to get his take on what the future holds for Quoin.

Q: Quoin Pharmaceuticals has had an exciting introduction to the market followed by some impressive company milestone announcements. It’s clear the company is focused on delivering long-term returns to investors. Can you talk about some of Quoin’s investment highlights?

A: Quoin is new to the market but a lot of work has gone on behind the scenes since the company was founded in 2018. Our lead asset, QRX003 for Netherton Syndrome, will enter clinical trials in the first half of this year. This therapeutic potentially qualifies for Rare Pediatric Drug Designation and we have received constructive and positive feedback from the FDA providing us with a clear path forward to approval. Approval of QRX003 could result in Quoin receiving a Priority Review Voucher with a potential, non-dilutive value of approximately $100 million. We have sufficient funding to complete our clinical work through the middle of 2023 with $25 million in committed funds from Altium Capital.

Q: Quoin appears to be very patient-focused. Can you tell us more about that?

A: Rare skin disorders such as Netherton Syndrome are debilitating and have no treatment beyond managing the symptoms, which include pain, redness, scaling, itching and infections. Living with a rare disease can be isolating and stressful for patients and their families, so we are 100% committed to doing everything we can to try to get our products to every single patient who needs them. As we work toward securing regulatory approvals in our core markets of the US and EU, we are also establishing relationships with distribution partners worldwide. To date we have signed exclusive agreements for QRX003 covering the MENA region, Russia and the Commonwealth of Independent States, Australasia and key markets in Latin America. We are in advanced discussions with potential partners in a number of additional territories, with a view to be able to reach all Netherton Syndrome patients globally.

Q: Can you tell us more about your lead candidate, QRX003 for Netherton Syndrome?

A: Put simply, Netherton Syndrome is the result of unregulated hyperactivity of skin proteases called kallikreins. This activity causes excessive skin shedding, leaving a patient’s skin very thin and susceptible to infections, atopic eczema and skin cancer. QRX003 is a broad spectrum serine protease with powerful anti-inflammatory and antioxidant action. It works by down regulating the activity of the kallikreins, reducing shedding and allowing skin architecture to recover. Finally, QRX003 provides a barrier over the skin, limiting penetration by unwanted environmental agents.

Q: Drug development is complex and challenging and many small biotechs struggle to go from clinical trials to getting product to patients. Why is Quoin different?

A: We are leveraging our extensive experience in this area to ensure that we are covering all of our bases along the development pathway. For example, we made sure right from the beginning that our contract manufacturers have the capacity to seamlessly move from clinical scale to commercial scale production with no change in facility or personnel required. In addition, we have engaged top level quality control consultants from day one who are ensuring that everything that is done on our behalf by our contractors is at the highest level of compliance.

Many small biotechs overlook these basic activities and focus solely on generating clinical trial results instead of the bigger picture of getting products to patients. We have a dual strategy. While we are advancing our therapeutics through clinical trials and the regulatory process, we are simultaneously working to create the most favorable market environment for our products once they are approved. Some examples of this are identifying patient populations and establishing strong relationships with the foundations that support these patients and their families. We are developing close ties with leading dermatology experts and treating physicians so that they are aware of the product and its development status.

Q: What is the market opportunity for QRX003?

A: We believe we have a long-term marketing opportunity for QRX003. It will be a ‘whole body, whole life’ topical therapeutic, that is applied to the patient’s entire skin surface once a day, every day, for life. We believe we are very well positioned to capture a very significant proportion of the entire Netherton Syndrome population and, in doing so, deliver excellent long term results for our shareholders.

Q: What is your strategy for commercializing Quoin’s products?

A: Our management team has deep experience in commercializing therapeutics, so we have a very clear strategy for getting our products to market. As mentioned, we are establishing distribution partnerships that will allow us to reach patient groups in most parts of the world, and we expect to announce a number of new partnerships in the first half of this year. There are several important value propositions about these partnerships that I’d like to highlight.

First, by establishing these partnerships early, it enables our partners to develop a deep understanding of the market in their respective territories, establish relationships with foundations, KOLs and also address reimbursement issues so that when the product is approved, they are fully ready to launch and maximize the commercial opportunity for the product. Second, many of the countries where we are establishing these partnerships have vibrant early access programs where the product can be supplied on a named patient basis in advance of formal regulatory approval. Programs such as these could begin to generate sales revenue for Quoin earlier than anticipated whilst the product is being used in a real world environment.

The second part of our strategy is addressing sales and distribution throughout our core markets of the US and Europe. In these regions, we intend to establish our own commercial infrastructure and we anticipate that fewer than 50 people will be more than sufficient to fully support both US and European markets. This highly compact sales infrastructure will enable us to successfully launch and commercialize our products whilst maximizing profitability. In addition, this same sales infrastructure will be positioned to commercialize each new product in our pipeline at no material incremental cost, further boosting our profitability.

Disclaimer

This communication was produced by PCG Digital Holdings, LLC, an affiliate of PCG Advisory Inc., (together “PCG”). PCG is not a registered or licensed broker-dealer nor investment adviser. No information contained in this communication constitutes an offer to sell, a solicitation of an offer to buy, or a recommendation of any security. PCG may be compensated by respective clients for publicizing information relating to its clients’ securities. See www.pcgadvisory.com/disclosures.

PCG Digital
[email protected]
646-863-6341

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/113039

Fintech

How to identify authenticity in crypto influencer channels

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Modern brands stake on influencer marketing, with 76% of users making a purchase after seeing a product on social media.The cryptocurrency industry is no exception to this trend. However, promoting crypto products through influencer marketing can be particularly challenging. Crypto influencers pose a significant risk to a brand’s reputation and ROI due to rampant scams. Approximately 80% of channels provide fake statistics, including followers counts and engagement metrics. Additionally, this niche is characterized by high CPMs, which can increase the risk of financial loss for brands.

In this article Nadia Bubennnikova, Head of agency Famesters, will explore the most important things to look for in crypto channels to find the perfect match for influencer marketing collaborations.

 

  1. Comments 

There are several levels related to this point.

 

LEVEL 1

Analyze approximately 10 of the channel’s latest videos, looking through the comments to ensure they are not purchased from dubious sources. For example, such comments as “Yes sir, great video!”; “Thanks!”; “Love you man!”; “Quality content”, and others most certainly are bot-generated and should be avoided.

Just to compare: 

LEVEL 2

Don’t rush to conclude that you’ve discovered the perfect crypto channel just because you’ve come across some logical comments that align with the video’s topic. This may seem controversial, but it’s important to dive deeper. When you encounter a channel with logical comments, ensure that they are unique and not duplicated under the description box. Some creators are smarter than just buying comments from the first link that Google shows you when you search “buy YouTube comments”. They generate topics, provide multiple examples, or upload lists of examples, all produced by AI. You can either manually review the comments or use a script to parse all the YouTube comments into an Excel file. Then, add a formula to highlight any duplicates.

LEVEL 3

It is also a must to check the names of the profiles that leave the comments: most of the bot-generated comments are easy to track: they will all have the usernames made of random symbols and numbers, random first and last name combinations, “Habibi”, etc. No profile pictures on all comments is also a red flag.

 

LEVEL 4

Another important factor to consider when assessing comment authenticity is the posting date. If all the comments were posted on the same day, it’s likely that the traffic was purchased.

 

2. Average views number per video

This is indeed one of the key metrics to consider when selecting an influencer for collaboration, regardless of the product type. What specific factors should we focus on?

First & foremost: the views dynamics on the channel. The most desirable type of YouTube channel in terms of views is one that maintains stable viewership across all of its videos. This stability serves as proof of an active and loyal audience genuinely interested in the creator’s content, unlike channels where views vary significantly from one video to another.

Many unauthentic crypto channels not only buy YouTube comments but also invest in increasing video views to create the impression of stability. So, what exactly should we look at in terms of views? Firstly, calculate the average number of views based on the ten latest videos. Then, compare this figure to the views of the most recent videos posted within the past week. If you notice that these new videos have nearly the same number of views as those posted a month or two ago, it’s a clear red flag. Typically, a YouTube channel experiences lower views on new videos, with the number increasing organically each day as the audience engages with the content. If you see a video posted just three days ago already garnering 30k views, matching the total views of older videos, it’s a sign of fraudulent traffic purchased to create the illusion of view stability.

 

3. Influencer’s channel statistics

The primary statistics of interest are region and demographic split, and sometimes the device types of the viewers.

LEVEL 1

When reviewing the shared statistics, the first step is to request a video screencast instead of a simple screenshot. This is because it takes more time to organically edit a video than a screenshot, making it harder to manipulate the statistics. If the creator refuses, step two (if only screenshots are provided) is to download them and check the file’s properties on your computer. Look for details such as whether it was created with Adobe Photoshop or the color profile, typically Adobe RGB, to determine if the screenshot has been edited.

LEVEL 2

After confirming the authenticity of the stats screenshot, it’s crucial to analyze the data. For instance, if you’re examining a channel conducted in Spanish with all videos filmed in the same language, it would raise concerns to find a significant audience from countries like India or Turkey. This discrepancy, where the audience doesn’t align with regions known for speaking the language, is a red flag.

If we’re considering an English-language crypto channel, it typically suggests an international audience, as English’s global use for quality educational content on niche topics like crypto. However, certain considerations apply. For instance, if an English-speaking channel shows a significant percentage of Polish viewers (15% to 30%) without any mention of the Polish language, it could indicate fake followers and views. However, if the channel’s creator is Polish, occasionally posts videos in Polish alongside English, and receives Polish comments, it’s important not to rush to conclusions.

Example of statistics

 

Wrapping up

These are the main factors to consider when selecting an influencer to promote your crypto product. Once you’ve launched the campaign, there are also some markers to show which creators did bring the authentic traffic and which used some tools to create the illusion of an active and engaged audience. While this may seem obvious, it’s still worth mentioning. After the video is posted, allow 5-7 days for it to accumulate a basic number of views, then check performance metrics such as views, clicks, click-through rate (CTR), signups, and conversion rate (CR) from clicks to signups.

If you overlooked some red flags when selecting crypto channels for your launch, you might find the following outcomes: channels with high views numbers and high CTRs, demonstrating the real interest of the audience, yet with remarkably low conversion rates. In the worst-case scenario, you might witness thousands of clicks resulting in zero to just a few signups. While this might suggest technical issues in other industries, in crypto campaigns it indicates that the creator engaged in the campaign not only bought fake views and comments but also link clicks. And this happens more often than you may realize.

Summing up, choosing the right crypto creator to promote your product is indeed a tricky job that requires a lot of resources to be put into the search process. 

Author Nadia Bubennikova, Head of agency  at Famesters

Author

Nadia Bubennikova, Head of agency at Famesters

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Fintech

Central banks and the FinTech sector unite to change global payments space

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The BIS, along with seven leading central banks and a cohort of private financial firms, has embarked on an ambitious venture known as Project Agorá.

Named after the Greek word for “marketplace,” this initiative stands at the forefront of exploring the potential of tokenisation to significantly enhance the operational efficiency of the monetary system worldwide.

Central to this pioneering project are the Bank of France (on behalf of the Eurosystem), the Bank of Japan, the Bank of Korea, the Bank of Mexico, the Swiss National Bank, the Bank of England, and the Federal Reserve Bank of New York. These institutions have joined forces under the banner of Project Agorá, in partnership with an extensive assembly of private financial entities convened by the Institute of International Finance (IIF).

At the heart of Project Agorá is the pursuit of integrating tokenised commercial bank deposits with tokenised wholesale central bank money within a unified, public-private programmable financial platform. By harnessing the advanced capabilities of smart contracts and programmability, the project aspires to unlock new transactional possibilities that were previously infeasible or impractical, thereby fostering novel opportunities that could benefit businesses and consumers alike.

The collaborative effort seeks to address and surmount a variety of structural inefficiencies that currently plague cross-border payments. These challenges include disparate legal, regulatory, and technical standards; varying operating hours and time zones; and the heightened complexity associated with conducting financial integrity checks (such as anti-money laundering and customer verification procedures), which are often redundantly executed across multiple stages of a single transaction due to the involvement of several intermediaries.

As a beacon of experimental and exploratory projects, the BIS Innovation Hub is committed to delivering public goods to the global central banking community through initiatives like Project Agorá. In line with this mission, the BIS will soon issue a call for expressions of interest from private financial institutions eager to contribute to this ground-breaking project. The IIF will facilitate the involvement of private sector participants, extending an invitation to regulated financial institutions representing each of the seven aforementioned currencies to partake in this transformative endeavour.

Source: fintech.globa

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TD Bank inks multi-year strategic partnership with Google Cloud

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TD Bank has inked a multi-year deal with Google Cloud as it looks to streamline the development and deployment of new products and services.

The deal will see the Canadian banking group integrate the vendor’s cloud services into a wider portion of its technology solutions portfolio, a move which TD expects will enable it “to respond quickly to changing customer expectations by rolling out new features, updates, or entirely new financial products at an accelerated pace”.

This marks an expansion of the already established relationship between TD Bank and Google Cloud after the group previously adopted the vendor’s Google Kubernetes Engine (GKE) for TD Securities Automated Trading (TDSAT), the Chicago-based subsidiary of its investment banking unit, TD Securities.

TDSAT uses GKE for process automation and quantitative modelling across fixed income markets, resulting in the development of a “data-driven research platform” capable of processing large research workloads in trading.

Dan Bosman, SVP and CIO of TD Securities, claims the infrastructure has so far supported TDSAT with “compute-intensive quantitative analysis” while expanding the subsidiary’s “trading volumes and portfolio size”.

TD’s new partnership with Google Cloud will see the group attempt to replicate the same level of success across its entire portfolio.

Source: fintechfutures.com

The post TD Bank inks multi-year strategic partnership with Google Cloud appeared first on HIPTHER Alerts.

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