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ResoTher Pharma receives a €2.5 million grant from European Innovation Council (EIC) to support a Phase 2a clinical study of their Lead Candidate RTP-026 for Myocardial Infarction

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HOLTE, Denmark, Nov. 6, 2023 /PRNewswire/ — ResoTher Pharma, a biotech company focused on developing life-saving options for patients suffering from cardiovascular disease, today announced that the company has received a €2.5 million grant from the European Innovation Council (EIC) to support the development of the company’s Lead Compound, RTP-026, in a Phase 2a clinical study in Myocardial Infarction.

 

The project focusing on development of Resother Pharmas RTP-026 compound is one of 47 projects selected to receive funding out of 648 full proposals submitted for evaluation to the EIC-accelerator program. The grant given to ResoTher Pharma is defined as a “Grant first,” meaning that the project will be considered for further support by the European Investment Bank upon completion of the Phase 2a study supported by the current grant.

“The EIC Grant is a major boost to our RTP-026 development program,” says Anders Kronborg, CEO of ResoTher Pharma. “It has made it possible to focus entirely on development, thereby accelerating the Phase 2a development path with the aim to initiate dosing in Q1 2024.”

RTP-026 is developed as a new and innovative way to modulate the inflammatory response that occurs in the heart during the recovery phase of a myocardial infarction. Especially in the subset of patients showing high inflammatory activity, there is a need for novel treatments to reduce the risk of reinfarction and other major cardiovascular events.

Following the completion of Phase 1 development, RTP-026 is ready to enter Phase 2a development with the aim of testing the potential of the compounds to modulate the hyperinflammatory response of the heart in patients undergoing percutaneous coronary intervention with the aim to reestablish blood supply in patients with acute myocardial infarction. In Phase 1 development conducted in healthy volunteers, the compound showed a very good safety profile when given as a single dose or in repeated dosing, with very good plasma exposure indicating a good safety profile relative to what is expected to be relevant exposure levels in patients.

The RTP-026 compound, an IP-protected analogue of the N-terminus of the Annexin A1 protein, is developed in collaboration with the Faculty of Medicine and Dentistry, Queen Mary University of London. The compound was designed and characterized in Professor Mauro Petretti’s laboratory at the William Harvey Research Institute.

The continued Phase 2 development, where the first step will be a Phase 2a dose range study to focus on safety and efficacy in a subset of high-risk ST-elevation Myocardial Infarction patients undergoing acute percutaneous coronary intervention will include active recruitment of patients at the Barts Heart Centre at St Bartholomew’s Hospital in London, one of Europe’s biggest coronary departments in London.

“The EIC grant has made it possible to proceed with Phase 2 development at Barts Heart Centre of a compound designed and characterized at Queen Mary. This important partnership demonstrates how our cutting-edge research in translational Pharmacology in the inflammatory and cardiovascular field moves from the lab to improving better health outcomes in East London and beyond,” says Professor Sir Mark Caulfield, MD, Vice Principal for Health, Queen Mary University of London, Director of the NIHR Barts Biomedical Research Centre.

“Resother Pharma previously received non-diluting funding from the Danish Innovation Fund and from Barts Charity, and continued collaboration with William Harvey Research Institute, a world-leading translational Pharmacology institute at Queen Mary University of London, has been highly valued,” says Anders Kronborg, CEO of ResoTher Pharma.

 

About ResoTher Pharma

ResoTher Pharma is a Danish privately held clinical-stage biotech company, focusing on the development of compounds that induce inflammatory resolution in cardiovascular diseases.

The company was founded in 2016 with the aim of developing compounds with the ability to promote pharmacological resolution in cardiovascular diseases. The company is privately owned by a group of prominent Danish investors. The company was founded by board member Jeppe Øvlesen and the head of the Scientific Advisory Board, Thomas Jonassen, MD. The co-inventor of the company’s lead compound, RTP-026, Professor Mauro Perretti, is also a shareholder in the company.

Mode of action of RTP-026: Upon formyl peptide type 2 receptor stimulation the RTP-026 compound induces a combination of anti-inflammatory and pre-resolving effects which in experimental models of myocardial infarction has profound effect not only on reducing the infarction size compared to placebo treatment, but importantly to restore cardiac function to a pre-infarction level.

 

For more information, please contact

Anders Kronborg, CEO
[email protected]
+4531516343
Or visit www.resotherpharma.com or follow us on LinkedIn.

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Invitation to presentation of EQT AB’s Q1 Announcement 2024

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STOCKHOLM, April 5, 2024 /PRNewswire/ — EQT AB’s Q1 Announcement 2024 will be published on Thursday 18 April 2024 at approximately 07:30 CEST. EQT will host a conference call at 08:30 CEST to present the report, followed by a Q&A session.

The presentation and a video link for the webcast will be available here from the time of the publication of the Q1 Announcement.

To participate by phone and ask questions during the Q&A, please register here in advance. Upon registration, you will receive your personal dial-in details.

The webcast can be followed live here and a recording will be available afterwards.

Information on EQT AB’s financial reporting

The EQT AB Group has a long-term business model founded on a promise to its fund investors to invest capital, drive value creation and create consistent attractive returns over a 5 to 10-year horizon. The Group’s financial model is primarily affected by the size of its fee-generating assets under management, the performance of the EQT funds and its ability to recruit and retain top talent.

The Group operates in a market driven by long-term trends and thus believes quarterly financial statements are less relevant for investors. However, in order to provide the market with relevant and suitable information about the Group’s development, EQT publishes quarterly announcements with key operating numbers that are relevant for the business performance (taking Nasdaq’s guidance note for preparing interim management statements into consideration). In addition, a half-year report and a year-end report including financial statements and further information relevant for investors is published. Finally, EQT also publishes an annual report including sustainability reporting.

Contact
Olof Svensson, Head of Shareholder Relations, +46 72 989 09 15
EQT Shareholder Relations, [email protected]

Rickard Buch, Head of Corporate Communications, +46 72 989 09 11
EQT Press Office, [email protected], +46 8 506 55 334

This information was brought to you by Cision http://news.cision.com

https://news.cision.com/eqt/r/invitation-to-presentation-of-eqt-ab-s-q1-announcement-2024,c3956826

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https://mb.cision.com/Main/87/3956826/2712771.pdf

Invitation to presentation of EQT AB’s Q1 Announcement 2024

https://news.cision.com/eqt/i/eqt-ab-group,c3285895

EQT AB Group

 

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Kia presents roadmap to lead global electrification era through EVs, HEVs and PBVs

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  • Kia drives forward transformation into ‘Sustainable Mobility Solutions Provider’
  • Roadmap enables Kia to proactively respond to uncertainties in mobility industry landscape, including changes in EV market
  • Company to expand EV line-up with more models; enhance HEV line-up to manage fluctuation in EV demand
    • Goal to sell 1.6 million EVs annually in 2030, introducing 15 models
    • PBV to play a key role in Kia’s growth, targeting 250,000 PBV sales annually by 2030 with PV5 and PV7 models
  • Kia to invest KRW 38 trillion by 2028, including KRW 15 trillion for future business
  • 2024 business guidance : KRW 101 tln in revenue with KRW 12 tln in operating profit; operating profit margin of 11.9% on sales of 3.2 million units globally
  • CEO reaffirms Kia’s commitment to ESG management

SEOUL, South Korea, April 5, 2024 /PRNewswire/ — Kia Corporation (Kia) today shared an update on its future strategies and financial targets at its CEO Investor Day in Seoul, Korea.

Based on its innovative achievements in the years since the announcement of mid-to-long-term business initiatives, Kia is focusing on updating its 2030 strategy announced last year and further strengthening its business strategy in response to uncertainties across the global mobility industry landscape.

During the event, Kia updated its mid-to-long-term business strategy with a focus on electrification, and its PBV business. Kia reiterated its 2030 annual sales target of 4.3 million units, including 1.6 million units of electric vehicles (EVs). The 2030 4.3 million annual sales target is 34.4 percent higher than the brand’s 2024 annual goal of 3.2 million units.

The company also plans to become a leading EV brand by selling a higher percentage of electrified models among its total sales, including hybrid electric vehicles (HEV), plug-in hybrid (PHEV), and battery EVs, projecting electrified model sales of 2.48 million units annually or 58 percent of Kia’s total sales in 2030.

“Following our successful brand relaunch in 2021, Kia is enhancing its global business strategy to further the establishment of an innovative EV line-up and accelerate the company’s transition to a sustainable mobility solutions provider,” said Ho Sung Song, President and CEO of Kia. “By responding effectively to changes in the mobility market and efficiently implementing mid-to-long-term strategies, Kia is strengthening its brand commitment to the wellbeing of customers, communities, the global society, and the environment.”

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BioVaxys Technology Corp. Provides Bi-Weekly MCTO Status Update

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VANCOUVER, BC, April 4, 2024 /PRNewswire/ — BioVaxys Technology Corp. (CSE: BIOV) (FRA: 5LB) (OTCQB: BVAXF) (the “Company“) is providing this bi-weekly update on the status of the management cease trade order granted on February 29, 2024 (the “MCTO“), by its principal regulator, the Ontario Securities Commission (the “OSC“), under National Policy 12-203 – Management Cease Trade Orders (“NP 12-203“), following the Company’s announcement on February 21, 2024 (the “Default Announcement“), that it was unable to file its audited annual financial statements for the year ended October 31, 2023, its management’s discussion and analysis of financial statements for the year ended October 31, 2023, its annual information form for the year ended October 31, 2023, and related filings (collectively, the “Required Annual Filings“). Under National Instrument 51-102, the Required Annual Filings were required to be made no later than February 28, 2024.

As a result of the delay in filing the Required Annual Filings, the Company was unable to file its interim financial statements for the three months ended January 31, 2024, its management’s discussion and analysis of financial statements for the three months ended January 31, 2024, and related filings (collectively, the “Required Interim Filings“). Under National Instrument 51-102, the Required Interim Filings were required to be made no later than April 1, 2024.

The Company anticipates filing the Required Annual Filings by April 30, 2024. The auditor of the Company requires additional time to complete its audit of the Company, including the Company’s recent acquisition of all intellectual property, immunotherapeutics platform technologies, and clinical stage assets of the former IMV Inc. that closed on February 16, 2024. In addition, the Company anticipates filing the Required Interim Filings immediately after the filing of the Required Annual Filings.

Except as herein disclosed, there are no material changes to the information contained in the Default Announcement. In addition, (i) the Company is satisfying and confirms that it intends to continue to satisfy the provisions of the alternative information guidelines under NP 12-203 and issue bi-weekly default status reports for so long as the delay in filing the Required Annual Filings and/or Required Interim Filings is continuing, each of which will be issued in the form of a press release; (ii) the Company does not have any information at this time regarding any anticipated specified default subsequent to the default in filing the Required Annual Filings and Required Interim Filings; (iii) the Company is not subject to any insolvency proceedings; and (iv) there is no material information concerning the affairs of the Company that has not been generally disclosed.

About BioVaxys Technology Corp.

BioVaxys Technology Corp. (www.biovaxys.com), a biopharmaceuticals company registered in British Columbia, Canada, is a clinical-stage biopharmaceutical company dedicated to improving patient lives with novel immunotherapies based on the DPX™ immune-educating technology platform and it’s HapTenix© ‘neoantigen’ tumor cell construct platform, for treating cancers, infectious disease, antigen desensitization, and other immunological fields. The Company’s clinical stage pipeline includes maveropepimut-S which is in Phase II clinical development for advanced Relapsed-Refractory Diffuse Large B Cell Lymphoma (DLBCL) and platinum resistant ovarian cancer, and BVX-0918, a personalized immunotherapeutic vaccine using it proprietary HapTenix© ‘neoantigen’ tumor cell construct platform which is soon to enter Phase I in Spain for treating refractive late-stage ovarian cancer. The Company is also capitalizing on its tumor immunology know-how and creation of a unique library of T-lymphocytes & other datasets post-vaccination with its personalized immunotherapeutic vaccines to utilize predictive algorithms and other technologies to identify new targetable tumor antigens. BioVaxys common shares are listed on the CSE under the stock symbol “BIOV” and trade on the Frankfurt Bourse (FRA: 5LB) and in the US (OTCQB: BVAXF). For more information, visit www.biovaxys.com and connect with us on X and LinkedIn.

ON BEHALF OF THE BOARD

Signed “James Passin
James Passin, Chief Executive Officer
Phone: +1 646 452 7054

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