Fintech PR
MGI: Closing the Cancer Care Gap with the Power of Precision Oncology
BERLIN, Feb. 4, 2024 /PRNewswire/ — According to American Cancer Society, Cancer causes about 1 in every 6 deaths globally, more than AIDS, tuberculosis, and malaria combined. Today, it is the first or second leading cause of death in most countries around the world. Technological advances in genomics have enabled the identification and improved understanding of causal factors and shed light on precision oncology.
February 4 marks World Cancer Day, an initiative aimed at promoting awareness on cancer as a public health issue and improving access to quality care, screening, early detection, therapy, and palliative care for those affected.
In this new era in precision oncology, researchers like Dr. Marie-Laure Yaspo from ALACRIS Theranostics (“ALACRIS”) and Dr. Xuan Gao and Dr.Huan Fang from GenePlus are working towards closing the care gap with evidence-based strategies in cancer control along the care continuum, from prevention to treatment, with help from MGI’s cutting-edge life science technologies.
ALACRIS innovates with its advanced tumor-agnostic molecular diagnostic test augmenting tailored treatment options
At ALACRIS Theranostics in Germany, co-founder and Chief Scientific Officer Dr. Marie-Laure Yaspo and her team are committed to provide every cancer patient with the highest standard of care through the Comprehensive Molecular Cancer Analysis (CMTA), a unique molecular diagnostic test designed to identify the best personalized treatment options for each patient, based on high-throughput sequencing of the exome (or genome) and transcriptome of their tumor.
“From past research in cancer genomics projects, we learned how complex and unique the molecular landscape of every tumor can be,” said Dr. Yaspo as she recalled her 12+ years in molecular genetics prior to establishing ALACRIS. “Only by collecting comprehensive information on the tumor landscape can we further develop and enhance personalized therapy.”
“Every patient is unique, every tumor is different,” added Dr. Yaspo. To capture this individuality, the CMTA technology integrates two layers of sequence data, DNA (genome or exome) and RNA (transcriptome), for a comprehensive analysis of the clinically relevant alterations in every tumor. In addition to mutations and chromosome copy number alterations, key features such as gene fusions, overexpressed oncogenes, immune microenvironment, and more provide essential information for the evaluation of the best therapeutic options.
“Starting from a tumor biopsy, the end-to-end Alacris-CMTA® process generates high-throughput sequencing data with MGI’s highly accurate and reliable platforms and deploys Alacris’s advanced bioinformatics analysis pipelines to deliver a comprehensive, interpreted tumor profiling report,” said Dr. Yaspo. “We interprete actionable alterations and match those with drug databases”, delivered a concise report guiding oncologists to design personalized therapies. The CMTA® fits the patient’s journey, and is particularly well suited for patients with refractory or rare cancers in need of treatment options. to improve their outcome.”
Back in 2022, MGI launched a Customer Experience Center at ALACRIS’s Berlin-based facility equipped with MGI’s DNBSEQ-G400* sequencer, MGISP-960 automation system and more. Not long after, in 2023, a new DNBSEQ-T7* sequencer was installed to further support the facility’s sequencing needs, including pediatric leukemias.
“The time that patients have is limited and precious. The faster we get sequencing samples analyzed, the sooner they can receive personalized treatment,” said Dr. Yaspo. “MGI platforms’ high flexibility and quick turnaround enable us to provide reliable diagnostics for a large number of patients. Its cost-effectiveness also makes it easier for more people to benefit from affordable and accessible cancer services, thereby contributing to better healthcare.”
GenePlus’ NGS total solution helps match cancer patients to precise therapy
Meanwhile in China, the team at GenePlus, including Dr. Xuan Gao and Dr. Huan Fang, Assistant Directors of the company’s Genomics Institute, has been studying tumor detection and intervention to help clinicians determine the safest and most effective treatment for cancer patients through clinical and scientific research.
“Having witnessed the pain and torment of someone close who suffered from cancer, I was determined to devote myself to cancer precision medicine,” said Dr. Gao. “In the 6+ years I’ve been in the field, high-throughput sequencing technology has rapidly promoted the development of tumor genomics research, giving us a better understanding of the genetic characteristics and molecular mechanisms of tumors, and thereby providing new targets and combination therapy options to alleviate patients’ suffering.”
Given the inherent complexity and heterogeneity of cancer, as well as its risks of genetic mutation, tumors are constantly evolving, which leads to drug resistance during treatment. Although the stratification of patients has been refined, there still lacks specific, tailor-made therapy options. At the same time, many advances in the field have yet to reach the masses due to high costs and insufficient clinical trial design and data. “MGI’s technology plays a critical role in helping us expanding precise tumor tests and genome-driven drug strategies for patients, including those who currently cannot use targeted therapy,” added Dr. Gao.
The GenePlus NGS total solution, which includes certified kits, library workshops, genetic sequencers, and the GeneBox informatic platform, facilitates faster, simpler and more reliable cancer sequencing. Benefitting from DNBSEQ’s high quality, accuracy and cost-effectiveness, the solution creates a pipeline of tumor precision medication, whole-process case, and pathogen detection. To date, it has been deployed in more than 30 key hospitals in China, where it is applied to the analysis of tumors and pathogens, serving over 550,000 patients in need of accurate diagnosis and treatment.
“Based on MGI’s DNBSEQ technology, our solution has low amplification error rate and high data utilization rate, which are crucial for ultra-deep sequencing of low-concentration or low-quality oncology samples,” said Dr. Fang. “We leverage this for targeting and immunotherapy guidance in advanced patients and drug sensitivity prediction and cancer minimum residual disease monitoring.”
The development of precision oncology has transformed how we approach the cancer care continuum – from prevention to detection, to diagnosis and treatment – for patients who are not only looking to survive but also to do so with an optimal quality of life. Supported by MGI, both CMTA® by ALACRIS and the GenePlus NGS total solution are laying the foundation for precise cancer control and ensuring all patients can enjoy effective, reliable, and affordable care for improved outcomes.
About MGI
MGI Tech Co. Ltd. (or its subsidiaries, together referred to MGI), headquartered in Shenzhen, is committed to building core tools and technology to lead life science through intelligent innovation. Based on its proprietary technology, MGI focuses on research & development, production and sales of sequencing instruments, reagents, and related products to support life science research, agriculture, precision medicine and healthcare. MGI is a leading producer of clinical high-throughput gene sequencers, and its multi-omics platforms include genetic sequencing, medical imaging, and laboratory automation. MGI’s mission is to develop and promote advanced life science tools for future healthcare. For more information, please visit the MGI website or connect with us on Twitter, LinkedIn or YouTube.
- For Research Use Only. Not for use in diagnostic procedures.
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DUBAI, UAE, Sept. 6, 2024 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, set out to make the community’s TOKEN2049 journey more rewarding. Gearing up for the most anticipated blockchain and Web3 event in the region, Bybit is thrilled to announce three bonus events to enable both attendees and remote fans to both be part of the experience.
The winning opportunities are open to both attendees of TOKEN2049 and followers from afar. Through trading and offline events, participants stand to get free tickets, a share of the $80,000 prize pool in airdrops and coupons, and Bybit merchandise.
Event 1: TOKEN2049 Treasure Express
From now to Sep. 26, 2024, Bybit users may register for the event and complete tasks by depositing and trading assets to earn lucky draw tickets. The wheel of fortune will turn to one of the three prizes:
1. A pair of tickets to TOKEN2049;
2. A share of the airdrop prize pool valued at $50,000 featuring the hottest tokens, including DOGS, PEPE, SOL, XRP, TON and USDT; or
3. Up to 50 USDT in spot coupons.
Even more rewards await in referrals and social media giveaways. For details, visit: TOKEN2049 Treasure Express
Event 2: Share and Unlock
From now to Sep. 30, 2024, unleash your social media magic for a chance to win a 10 USDT spot trading coupon. Share a Bybit blog link and your thoughts on Bybit and Web3. Remember to tag @Bybit_Official and use the hashtag #UnlockWeb3Future and submit the form with us here: #UnlockWeb3Future at TOKEN2049 with Bybit
Event 3: Meet us offline at TOKEN2049
Spot our logo at TOKEN2049 and capture a photo at the Bybit booth (M50) to win Bybit merchandise. Remember to share to your social media channels and use the right hashtag. For details, visit: #UnlockWeb3Future at TOKEN2049 with Bybit
An advocate for a sustainable Web3 ecosystem, Bybit will be featured prominently at TOKEN2049 on a series of keynote panels, thought leadership and community events, and booth M50.
#Bybit / #TheCryptoArk
About Bybit
Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving over 40 million users. Established in 2018, Bybit provides a professional platform where crypto investors and traders can find an ultra-fast matching engine, 24/7 customer service, and multilingual community support. Bybit is a proud partner of Formula One’s reigning Constructors’ and Drivers’ champions: the Oracle Red Bull Racing team.
For more details about Bybit, please visit Bybit Press.
For media inquiries, please contact: [email protected]
For more information, please visit: https://www.bybit.com
For updates, please follow: Bybit’s Communities and Social Media
Discord | Facebook | Instagram | LinkedIn | Reddit | Telegram | TikTok | X | Youtube
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DUBAI, UAE, Sept. 6, 2024 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, is excited to announce it’s among the first to be granted consent to a full authorization by the Astana Financial Service Authority (AFSA). This milestone brings Bybit closer to becoming a fully regulated Digital Asset Trading Facility (DATF).
As part of a rigorous process, Bybit Kazakhstan has passed a full AML check, business conduct audit, and detailed compliance inspections. This is part of Bybit’s focus on securing new user opportunities in Kazakhstan and the broader Commonwealth of Independent States (CIS) region.
“Kazakhstan has become a key player in the global crypto ecosystem, and we are thrilled to be expanding our services in such a dynamic market,” said Ben Zhou, co-founder and CEO of Bybit. “We are committed to bringing our cutting-edge technology, security, and transparency to crypto traders in Kazakhstan, ensuring they can access the best possible tools and services to thrive in this fast-growing industry.”
Once the full license is in place, Bybit Kazakhstan will offer various digital assets related products and services. The expansion into Kazakhstan aligns with Bybit’s mission to provide reliable and transparent services, catering to the unique needs of crypto traders and investors in the region.
This development follows Bybit’s receipt of its initial operating and custody licenses from AFSA in June 2023, reinforcing its commitment to local regulatory requirements. Bybit’s ongoing efforts to strengthen its presence in Kazakhstan underscore its belief in responsible growth and ensuring a compliant and secure trading environment.
Kazakhstan has quickly emerged as a hub for crypto innovation, and Bybit is proud to play a leading role in fostering this development. For example, Bybit hosted a “Foundations of Blockchain, Web3 and Crypto Exchange Activities” course for Banks of Kazakhstan in 2024. This event was part of Bybit’s drive to make blockchain education more accessible in the CIS region.
By securing this full authorization, Bybit is poised to enhance crypto adoption, provide institutional-grade security, and offer advanced trading features to its growing regional user base.
#Bybit / #TheCryptoArk
About Bybit
Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving over 40 million users. Established in 2018, Bybit provides a professional platform where crypto investors and traders can find an ultra-fast matching engine, 24/7 customer service, and multilingual community support. Bybit is a proud partner of Formula One’s reigning Constructors’ and Drivers’ champions: the Oracle Red Bull Racing team.
For more details about Bybit, please visit Bybit Press.
For media inquiries, please contact: [email protected]
For more information, please visit: https://www.bybit.com
For updates, please follow: Bybit’s Communities and Social Media
Discord | Facebook | Instagram | LinkedIn | Reddit | Telegram | TikTok | X | Youtube
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View original content:https://www.prnewswire.co.uk/news-releases/bybit-expands-global-reach-receives-formal-consent-for-full-authorization-in-kazakhstan-302240634.html
Fintech PR
Integrum ESG and CSRHub enable fund managers to monitor both long-term trends and short-term movements in ESG ratings for companies, across a 10-year time series
LONDON, Sept. 6, 2024 /PRNewswire/ — Integrum ESG, the leading alternative ESG data provider, has today announced the launch of their Consensus ESG Ratings module.
Just as investors monitor movements in consensus earnings estimates or credit ratings, investors now are aware of the demand for the ability to monitor long-term trends and short-term movements in consensus ESG ratings.
This new feature enables Integrum ESG’s asset manager clients to now see the consensus ESG score for any company, either as an absolute rating or a relative percentile ranking, across a 10-year time series.
These scores will indicate to any investor what the capital markets have ‘priced in’ for a company’s ESG performance, allowing users to quickly understand the market’s view on a company and easily conduct relative ESG analysis on the positions they hold within their Portfolio.
This regularly updated data is provided by CSRHub, the world’s leading provider of consensus ESG ratings. CSRHub has spent years aggregating and normalising a vast range of licensed sources – from large ESG ratings firms such as MSCI, ISS, S&P Global, and Sustainalytics to specialists such as CDP and Better World Companies.
Shai Hill, Founder and CEO of Integrum ESG, commented: “Many investors have told us they want a sense of ‘what is priced in’ in terms of a company’s ESG performance, so they can compare this to what anyone ESG ratings firm is saying. CSRHub is the only firm to have credibly achieved this, thanks to a model refined over years and a vast data lake – so we are delighted to be partnering with them.”
Bahar Gidwani, Co-Founder of CSRHub, added: “Investors need to fine tune their ESG-related investment strategies to improve their returns and better match the preferences of their clients. Combining CSRHub’s expert outside-in, consensus view of ESG with Integrum ESG’s detailed real-time data stream provides a strong solution for these needs.”
About Integrum ESG
Integrum ESG is the leading alternative ESG data and ratings platform for investors, blending human analysis and award-winning artificial intelligence models to capture, verify and display granular and relevant ESG data for analysis and assessment. Their Platform allows clients to dissect ESG scores, real-time sentiment, and more with a variety of unique-to-market features, empowering industry professionals and investors and giving them complete oversight of ESG risk across their portfolio.
For more information, visit www.integrumesg.com
About CSRHub
CSRHub offers the most comprehensive global set of Consensus ESG (Environmental, Social, and Governance) ratings, information, and tools. CSRHub’s business intelligence system measures the ESG business impact that drives corporate and investor sustainability decisions. Founded in 2007, CSRHub covers 56,545 public and private companies, and provides ESG performance scores on over 37,899 companies from 135 industries in 210 countries. Our Big Data platform uses algorithms to aggregate, normalize and weight ESG metrics from 957 sources to produce a strong consensus signal on corporate sustainability performance.
For more information, visit www.csrhub.com
Media Contact
Harish Karunalingam
Integrum ESG
[email protected]
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